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362199

Sigma-Aldrich

α₂-HS-Glycoprotein, Human Plasma

Sinónimos:

Fetuin, Human

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.25

assay

≥90% (SDS-PAGE)

Quality Level

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

water: soluble

shipped in

ambient

storage temp.

−20°C

General description

Native α2-HS-glycoprotein from human plasma. Plasma protein that is also found in the extracellular matrix. Synthesized in liver and enriched in bone. Its concentration dynamically changes under various physiological conditions. Functions as an opsonin for cationic-deactivating molecules in macrophages.
Native α2-HS-glycoprotein from human plasma. Plasma protein that is also found in the extracellular matrix. Synthesized in the liver and enriched in bone. Concentration dynamically changes under various physiological conditions. Functions as an opsonin for cationic-deactivating molecules in macrophages.

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from 200 mM NaCl, 20 mM Tris-HCl, pH 8.0.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C).

Other Notes

Wang, H., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 14429.
Boyan, B.D., et al. 1992. Bone Miner. 17, 263.
Yang, F., et al. 1991. Bone 12, 7.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

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Edward R Smith et al.
PloS one, 8(4), e60904-e60904 (2013-04-12)
The formation of fetuin-A-containing calciprotein particles (CPP) may facilitate the clearance of calcium phosphate nanocrystals from the extracellular fluid. These crystals may otherwise seed extra-osseous mineralization. Fetuin-A is a partially phosphorylated glycoprotein that plays a critical role in stabilizing these

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