137151

2- Mercaptoetanol

EMPROVE^® EVOLVE

• Sinónimos: β-Mercaptoetanol, 2- Hidroxietilmercaptano, BME, Tioetilenglicol
• Fórmula lineal: HSCH₂CH₂OH
• Número de CAS: 60-24-2
• Peso molecular: 78.13
• Beilstein: 773648
• Número MDL: MFCD00004890
• Código UNSPSC: 12161504

Propiedades

• densidad de vapor: 2.69 (vs air)
• Nivel de calidad: 400
• presión de vapor: 1 mmHg ( 20 °C)
• Formulario: liquid
• lim. expl.: 18 %
• concentración: 14.3 M (pure liquid); 99.0-101.0 % (w/w)
• impurezas: ≤1.0% related substances (GC) 2,2-Dithiodiethanol
• índice de refracción: n20/D 1.500 (lit.)
• bp: 157 °C (lit.)
• densidad: 1.114 g/mL at 25 °C (lit.)
• idoneidad: corresponds for identity (IR)
• aplicaciones: pharma/biopharma processes
• temp. de almacenamiento: 2-8°C
• cadena SMILES: OCCS
• InChI: 1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
• Clave InChI: DGVVWUTYPXICAM-UHFFFAOYSA-N

Descripción

Descripción general

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Aplicación

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

Nota de análisis

purity (GC) ≥99.0%

Información legal

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS05,GHS06,GHS08,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H301 + H331 - H310 - H315 - H317 - H318 - H361fd - H373 - H410
• Consejos de prudencia: P201 - P260 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P305 + P351 + P338 + P310
• Clasificaciones de peligro: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
• Código de clase de almacenamiento: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°C): 74 °C - closed cup