09-230

Anti-phospho-Raptor (Thr706) Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: P150 target of rapamycin (TOR)-scaffold protein, p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats, regulatory associated protein of mTOR
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: canine, human
• reactividad de especies (predicha por homología): horse (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), dog (based on 100% sequence homology), rat (based on 100% sequence homology)
• técnicas: dot blot: suitable; western blot: suitable
• Nº de acceso NCBI: NP_065812
• Nº de acceso UniProt: Q8N122
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: phosphorylation (pThr706)
• Información sobre el gen: bovine ... Rptor(507056) ; human ... RPTOR(57521)

Descripción

Descripción general

Raptor is a subunit of mTORC1 which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Within mTORC1, Raptor positively regulates mTORC1 activity and functions as a scaffold for recruiting mTORC1 substrates.

Especificidad

This antibody recognizes Raptor phosphorylated at Thr706.

Inmunógeno

Epitope: Ser706

KLH-conjugated linear peptide corresponding to human Raptor phosphorylated at and around Thr706.

Aplicación

Detect phospho-Raptor (Thr706) using this Anti-phospho-Raptor (Thr706) Antibody validated for use in WB, DB.

Calidad

Evaluated by Dot Blot in modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected Raptor in modified and non-modified peptides of phosphorylated and non-phosphorlyated Raptor protein.

Descripción de destino

~ 150 kDa

Forma física

Purified rabbit serum in PBS with 0.05% sodium azide.

Nota de análisis

Control
Modified and non modified peptides of phosphorylated and non-phosphorlyated Raptor protein

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable