Recognizes both Abl and BCR-Abl when phosphorylated on tyrosine residue corresponding to Tyr245 in Abl.
Immunogen
KLH-conjugated peptide corresponding to amino acid region encompassing human c-Abl Tyr245.
Application
Anti-phospho-Abl (Tyr245) Antibody is an antibody against phospho-Abl (Tyr245) for use in ELISA & WB.
Research Category Signaling
Research Sub Category Cytoskeletal Signaling
General Post-translation Modification
Quality
Routinely evaluated by immunoblot.
Target description
145 kDa (210 kDa for BCR-Abl)
Physical form
ImmunoAffinity Purified
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
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Ret is a receptor tyrosine kinase for the GDNF family of ligands and plays important roles during nervous system development for cell proliferation, cell migration and neurite growth. Signaling initiated from intracellular tyrosine 1062, by recruitment of several different phosphotyrosine
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