860679P
Avanti
C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z))
Avanti Research™ - A Croda Brand 860679P, powder
Sinónimos:
N-nervonoyl-D-erythro-sphingosine (d7)
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About This Item
Fórmula empírica (notación de Hill):
C42H74D7NO3
Número de CAS:
Peso molecular:
655.14
Número MDL:
Código UNSPSC:
12352100
NACRES:
NA.25
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Formulario
powder
envase
pkg of 1 × 1 mg (860679P-1mg)
fabricante / nombre comercial
Avanti Research™ - A Croda Brand 860679P
Condiciones de envío
dry ice
temp. de almacenamiento
−20°C
cadena SMILES
OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]
Clave InChI
VJSBNBBOSZJDKB-PVDQZAGSSA-N
Descripción general
C24:1 Ceramide (d18:1/24:1) is a synthetic ceramide derived from sphingosine with nervonic acid (a monounsaturated analog of lignoceric acid (24:0)).[1] C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) is a deuterated derivative of C24:1 Ceramide (d18:1/24:1).
Aplicación
C24:1 Ceramide-d7 (d18:1-d7/24:1(15Z)) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24:1 ceramide in skeletal muscle.[2] It has also been used as a standard to measure C40-C44 ceramides in zebrafish brain and human embryonic kidney cell line (HEK293) by thermo q-exactive plus quadrupole-orbitrap mass spectrometery.[3]
Acciones bioquímicas o fisiológicas
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma aids the prognosis of fatal outcome of coronary artery disease. C24:1 Ceramide (d18:1/24:1) in a stable isotope form is suitable for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.[4]
Envase
5 mL Amber Glass Screw Cap Vial (860679P-1mg)
Información legal
Avanti Research is a trademark of Avanti Polar Lipids, LLC
también adquirido normalmente con este producto
Referencia del producto
Descripción
Precios
Código de clase de almacenamiento
11 - Combustible Solids
Punto de inflamabilidad (°F)
No data available
Punto de inflamabilidad (°C)
No data available
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Certificados de análisis (COA)
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Paul T Reidy et al.
The Journal of physiology, 596(21), 5217-5236 (2018-09-09)
Insulin sensitivity (as determined by a hyperinsulinaemic-euglyceamic clamp) decreased 15% after reduced activity. Despite not fully returning to baseline physical activity levels, insulin sensitivity unexpectedly, rebounded above that recorded before 2 weeks of reduced physical activity by 14% after the recovery
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Tejia Zhang et al.
Scientific reports, 9(1), 19939-19939 (2019-12-29)
Extensive characterisations of the zebrafish genome and proteome have established a foundation for the use of the zebrafish as a model organism; however, characterisation of the zebrafish lipidome has not been as comprehensive. In an effort to expand current knowledge
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain
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