850446C

14:0-18:0 PC

1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine, chloroform

• Sinónimos: 1-tetradecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine; MSPC; PC(14:0/18:0)
• Fórmula empírica (notación de Hill): C₄₀H₈₀NO₈P
• Número de CAS: 76343-22-1
• Peso molecular: 734.04
• Número MDL: MFCD00674323
• Código UNSPSC: 51191904
• NACRES: NA.25

Propiedades

• Ensayo: >99% (TLC)
• Formulario: liquid
• envase: pkg of 1 × 2.5 mL (850446C-25mg); pkg of 2 × 4 mL (850446C-200mg)
• fabricante / nombre comercial: Avanti Research^™ - A Croda Brand 850446C
• concentración: 10 mg/mL (850446C-25mg); 25 mg/mL (850446C-200mg)
• tipo de lípido: cardiolipins; phospholipids
• Condiciones de envío: dry ice
• temp. de almacenamiento: −20°C
• cadena SMILES: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C40H80NO8P/c1-6-8-10-12-14-16-18-19-20-21-23-25-27-29-31-33-40(43)49-38(37-48-50(44,45)47-35-34-41(3,4)5)36-46-39(42)32-30-28-26-24-22-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
• Clave InChI: TYAQXZHDAGZOEO-KXQOOQHDSA-N

Descripción

Descripción general

Phosphatidylcholine (PC) is one of the most important constituent of colon′s mucosal layer.[1] 14:0-18:0 PC (1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine) is an asymmetrical lipid.[2]

Aplicación

14:0-18:0 PC (1-myristoyl-2-stearoyl-sn-glycero-3-phosphocholine) may be used:

• in lipid bilayers to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC)[3]
• as an asymmetrical lipid in liposomes to study the impact of bilayer area and lipid geometry on the design of liposomes as liposomal solubilizing agents[2]
• to prepare a low temperature-sensitive liposome encapsulating thrombolytics to assess thrombolytic activity following hyperthermia[4]

Acciones bioquímicas o fisiológicas

Phosphatidylcholine (PC) can form a hydrophobic surface in the mucus by acting as a surfactant to inhibit the penetrance of bacteria.[1]

Envase

5 mL Clear Glass Sealed Ampule (850446C-200mg)

5 mL Clear Glass Sealed Ampule (850446C-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Pictogramas: GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H302,H315,H319,H331,H336,H351,H361d,H372
• Consejos de prudencia: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Órganos de actuación: Liver,Kidney, Respiratory system
• Código de clase de almacenamiento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): does not flash
• Punto de inflamabilidad (°C): does not flash