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640006P

Avanti

DMABA-d6 NHS Ester

Avanti Research™ - A Croda Brand

Sinónimos:

4-(dimethylamino)benzoic acid N-hydroxysuccinimide ester-d6

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About This Item

Fórmula empírica (notación de Hill):
C13H8D6N2O4
Número de CAS:
1175002-04-6
Peso molecular:
268.30
UNSPSC Code:
12352211
NACRES:
NA.25

description

4-[di(methyl-d3)amino]-2,5-dioxo-1-pyrrolidinyl ester benzoic acid-d6

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (640006P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=C(ON(C(CC1)=O)C1=O)C2=CC=C(N(C([2H])([2H])[2H])C([2H])([2H])[2H])C=C2

General description

The DMABA NHS ester reagents were developed by Dr. Robert Murphy′s laboratory at the University of Colorado in order to create PE derivatives where all subclasses and potentially oxidized products could be universally detected using a common precursor ion in the positive ion mode by Mass Spectrometry.

Biochem/physiol Actions

Deuterium enriched 4-(dimethylamino) benzoic acid (DMABA) N-hydroxysuccinimide (NHS) ester reagents (d0, d4, d6, d10) derivatize the primary amine group of lipids, such as glycerophosphoethanolamine (PE) lipid species.

Packaging

5 mL Amber Glass Screw Cap Vial (640006P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Recently, a derivative of PE, namely the 4-(dimethylamino)benzoic acid derivative has been developed with various isotope labeled variants that provided a universal precursor ion scan for diacyl, ether and plasmalogen PE lipids that can not be accomplished otherwise. This derivative
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Analytical chemistry, 81(16), 6633-6640 (2010-03-27)
A set of four (D(0), D(4), D(6), and D(10)) deuterium enriched 4-(dimethylamino)benzoic acid (DMABA) N-hydroxysuccinimide (NHS) ester reagents was developed that react with the primary amine group of glycerophosphoethanolamine (PE) lipids to create derivatives where all subclasses of DMABA labeled
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