682144

(R)-(–)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane

96%

• Sinónimos: (R)-Phanephos
• Fórmula empírica (notación de Hill): C₄₀H₃₄P₂
• Número de CAS: 364732-88-7
• Peso molecular: 576.65
• Número MDL: MFCD03094575
• Código UNSPSC: 12352002
• ID de la sustancia en PubChem: 24885681
• NACRES: NA.22

Propiedades

• Ensayo: 96%
• Formulario: solid
• actividad óptica: [α]/D -34±4°, c = 1 in chloroform
• mp: 222-226 °C
• grupo funcional: phosphine
• cadena SMILES: P(c7ccccc7)(c6ccccc6)c1c2ccc(c1)CCc3c(cc(cc3)CC2)P(c5ccccc5)c4ccccc4
• InChI: 1S/C40H34P2/c1-5-13-35(14-6-1)41(36-15-7-2-8-16-36)39-29-31-21-25-33(39)27-23-32-22-26-34(28-24-31)40(30-32)42(37-17-9-3-10-18-37)38-19-11-4-12-20-38/h1-22,25-26,29-30H,23-24,27-28H2
• Clave InChI: GYZZZILPVUYAFJ-UHFFFAOYSA-N

Descripción

Aplicación

(R)-(-)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane may be used as a ligand in the following processes:

• Enantioselective reductive cyclization of 1,6-enynes via asymmetric hydrogenation in the presence of a rhodium catalyst to form alkylidene-substituted heterocycles.[1]
• Asymmetric hydroboration of 3,3-disubstituted cyclopropenes to form 2,2-disubstituted cyclopropyl boronates.[2]
• Asymmetric ring-opening reactions of azabenzonorbornadienes in the presence of zinc(II) triflate and palladium(II) acetate to form aminodihydronaphthalenes.[3]

Efficient ligand for asymmetric hydrogentation of dehydroamino acids, methyl esters and keytones.[4][5]

Información legal

Sold in collaboration with Johnson Matthey Catalyst for research purposes only. US5874629 and any patents arising therefrom apply.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves