153796
Myristic acid
≥99.5%
Sinónimos:
1-Tridecanecarboxylic acid, C14:0, NSC 5028, Tetradecanoic acid
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About This Item
Fórmula lineal:
CH3(CH2)12COOH
Número de CAS:
Peso molecular:
228.37
Beilstein/REAXYS Number:
508624
EC Number:
MDL number:
UNSPSC Code:
12352103
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assay
≥99.5%
bp
250 °C/100 mmHg (lit.)
mp
52-54 °C (lit.)
SMILES string
CCCCCCCCCCCCCC(O)=O
InChI
1S/C14H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h2-13H2,1H3,(H,15,16)
InChI key
TUNFSRHWOTWDNC-UHFFFAOYSA-N
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Tobias Seyberth et al.
Journal of medicinal chemistry, 49(5), 1754-1765 (2006-03-03)
Lipoproteins from gram-positive and -negative bacteria, mycoplasma, and shorter synthetic lipopeptide analogues activate cells of the innate immune system via the Toll-like receptor TLR2/TLR1 or TLR2/TLR6 heterodimers. For this reason, these compounds constitute highly active adjuvants for vaccines either admixed
Balasubramanian Narasimhan et al.
Bioorganic & medicinal chemistry letters, 16(11), 3023-3029 (2006-03-24)
A series of esters and amides of myristic acid was synthesized and tested in vitro for antibacterial activity against gram-positive and gram-negative bacteria. All the compounds showed activity comparable to that of the standard drug, ciprofloxacin. The structural characteristics governing
Bhadreshkumar B Maisuria et al.
Bioorganic & medicinal chemistry, 19(9), 2918-2926 (2011-04-16)
Homologous dicarboxyl dendritic amphiphiles-RCONHC(CH(3))(CH(2)CH(2)COOH)(2), 4(n); and ROCONHC(CH(3))(CH(2)CH(2)COOH)(2), 5(n), where R=n-C(n)H(2)(n)(+1) and n=13-22 carbon atoms-were synthesized. Critical micelle concentrations (CMCs) in aqueous triethanolamine solutions and at pH 7.4 were measured along with hemolytic activity (effective concentrations, EC(10)) in phosphate-buffered saline (PBS).
Marcy J Balunas et al.
Journal of natural products, 69(4), 700-703 (2006-04-29)
Natural product drug discovery efforts frequently utilize noncellular screening assays. Fatty acids are commonly found in natural product extracts, and some have been shown to interfere with noncellular assays. Several pure fatty acids were tested using a noncellular aromatase assay
Yunbao Liu et al.
Journal of natural products, 73(7), 1193-1195 (2010-06-23)
Antioxidants scavenge free radicals, singlet oxygen, and electrons in cellular redox reactions. The yellow MTT [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide] is reduced to a purple formazan by mitochondrial enzymes. NADPH is the basis of established in vitro cell viability assays. An antioxidant assay
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