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Merck

PRKCD

protein kinase C, delta

Sinónimos:
MAY1, PKCD, nPKC-delta
Especie:
ID UniProtKB:
ID del gen:
  • Human(5580) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18753) protein kinase C, delta
  • Rat(170538) protein kinase C, delta
  • domestic cat(101087716) protein kinase C, delta
  • chicken(415905) protein kinase C, delta
  • domestic guinea pig(100726624) protein kinase C, delta
  • naked mole-rat(101718422) protein kinase C, delta
  • sheep(101107639) protein kinase C, delta
  • Domestic Rabbit(100008966) protein kinase C, delta
  • cow(505708) protein kinase C, delta
  • sheep(100294651) protein kinase C, delta
  • dog(494005) protein kinase C, delta

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Ácido oleico, ≥99% (GC),
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-phospho-PKCδ (Ser664) Antibody, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
western blot
Anti-PKC delta Antibody, clone 7I5U6, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Phorbol 12,13-dibutyrate, ≥98% (TLC), powder,
Especie
mouse
H-7 dihydrochloride, ≥98% (HPLC),
Especie
human
Tamoxifen citrate salt, ≥99%,
Especie
human
Ácido oleico, ≥99% (GC),
Especie
human
UCN-01, ≥97% (HPLC), powder,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
PKCδ Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 2-end, of human PKCδ. For use in Kinase Assays.,
Especie
human
Protein Kinase Cδ isozyme human, >95% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PRKCD,
Especie
human
MISSION® esiRNA, targeting mouse Prkcd,
Especie
mouse