LRRK2
leucine-rich repeat kinase 2
Sinónimos:
AURA17, DARDARIN, PARK8, RIPK7, ROCO2
Especie:
Human LRRK2 (120892), Mouse Lrrk2 (66725), Rat Lrrk2 (300160), Zebrafish lrrk2 (559366), dog LRRK2 (486608), cow LRRK2 (535652), domestic cat LRRK2 (101096157), sheep LRRK2 (101111447), naked mole-rat Lrrk2 (101708809), chicken LRRK2 (427844)
ID UniProtKB:
ID del gen:
- Human(120892) Summary: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008]
- Mouse(66725) leucine-rich repeat kinase 2
- Rat(300160) leucine-rich repeat kinase 2
- Zebrafish(559366) leucine-rich repeat kinase 2
- dog(486608) leucine-rich repeat kinase 2
- cow(535652) leucine-rich repeat kinase 2
- domestic cat(101096157) leucine-rich repeat kinase 2
- sheep(101111447) leucine-rich repeat kinase 2
- naked mole-rat(101708809) leucine-rich repeat kinase 2
- chicken(427844) leucine-rich repeat kinase 2
- domestic guinea pig(100730338) leucine-rich repeat kinase 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-LRRK2 Antibody, clone N138/6, clone N138/6, from mouse,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Anti-LRRK2/PARK8 Antibody, clone 1C17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, horse, human, monkey, mouse, porcine
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-LRRK2 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Phospho-LRRK2-S935 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Dardarin Antibody, serum, Chemicon®,
Reactividad de especies
human, mouse
Aplicación
ELISA
western blot
western blot
Proteins
Referencia del producto
Descripción
Especie
LRRK2 Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human LRRK2, amino acids 970-end. For use in Kinase Assays.,
Especie
human