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Merck

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Sinónimos:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Especie:
ID UniProtKB:
ID del gen:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Metoclopramide, VETRANAL®, analytical standard,
Especie
human
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human
SR 57227A, solid,
Especie
human
Quipazine maleate salt, ,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
DCEBIO, ≥98% (HPLC), solid,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Serotonin hydrochloride, powder,
Especie
human
Serotonin creatinine sulfate monohydrate, powder,
Especie
human
Ondansetron hydrochloride dihydrate, ≥98% (HPLC), powder,
Especie
human
1-(4-Chlorophenyl)piperazine, ≥98.0% (GC),
Especie
rat
Ondansetron hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Mifepristone, ≥98%,
Especie
human, mouse, rat
Harmaline, ≥95%,
Especie
human, rat

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Especie
human

Small Molecule - Metabolite

Referencia del producto
Descripción
Especie
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Especie
human

Small Molecule - Precursor

Referencia del producto
Descripción
Especie
5-Hydroxy-L-tryptophan, powder,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Htr3a,
Especie
mouse
MISSION® esiRNA, targeting human HTR3A,
Especie
human