CDK1
cyclin-dependent kinase 1
Sinónimos:
CDC2, CDC28A, P34CDC2
Especie:
Human CDK1 (983), Mouse Cdk1 (12534), Rat Cdk1 (54237), dog CDK1 (488997), Zebrafish cdk1 (80973), chicken CDK1 (396252), naked mole-rat Cdk1 (101717463), domestic guinea pig Cdk1 (100735946), Goat CDK1 (100861361), cow CDK1 (281061)
ID UniProtKB:
ID del gen:
- Human(983) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(12534) cyclin-dependent kinase 1
- Rat(54237) cyclin-dependent kinase 1
- dog(488997) cyclin-dependent kinase 1
- Zebrafish(80973) cyclin-dependent kinase 1
- chicken(396252) cyclin-dependent kinase 1
- naked mole-rat(101717463) cyclin-dependent kinase 1
- domestic guinea pig(100735946) cyclin-dependent kinase 1
- Goat(100861361) cyclin-dependent kinase 1
- cow(281061) cyclin-dependent kinase 1
- sheep(100216432) cyclin-dependent kinase 1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-phospho-Cdk1 (Thr14, Tyr15)Antibody, clone CP3.2, clone CP3.2, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
western blot
western blot
Anti-CDC2 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-CDK1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anticuerpo anti-Cdk1, clon A17.1.1, clone A17.1.1, Chemicon®, from mouse,
Reactividad de especies
xenopus, chicken, human, mouse, rat
Aplicación
activity assay
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Phospho-CDK1-Y15 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
esiRNA
Referencia del producto
Descripción
Especie