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M3379

Sigma-Aldrich

DL-Methioninol

≥95%

Synonym(s):

4-Methylmercapto-2-amino-1-butanol

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About This Item

Empirical Formula (Hill Notation):
C5H13NOS
CAS Number:
16720-80-2
Molecular Weight:
135.23
MDL number:
MFCD00068312
UNSPSC Code:
12352200
PubChem Substance ID:
24896835
NACRES:
NA.26

Product Name

DL-Methioninol, ≥95%, viscous liquid

Assay

≥95%

form

viscous liquid

color

colorless to faint yellow

application(s)

cell analysis

SMILES string

CSCCC(N)CO

InChI

1S/C5H13NOS/c1-8-3-2-5(6)4-7/h5,7H,2-4,6H2,1H3

InChI key

MIQJGZAEWQQAPN-UHFFFAOYSA-N

Biochem/physiol Actions

Methioninol is a methionine derivative that has been shown to inhibit SDK and TREK-1 channels in COS cells.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKBQ4229V
MKBN7058
MKBK4197
048K1210
034K0972

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S A Baker et al.
British journal of pharmacology, 153(6), 1259-1271 (2008-01-22)
During the bladder filling phase, the volume of the urinary bladder increases dramatically, with only minimal increases in intravesical pressure. To accomplish this, the smooth muscle of the bladder wall must remain relaxed during bladder filling. However, the mechanisms responsible
Homar S Barcena et al.
Organic letters, 5(5), 709-711 (2003-02-28)
One-electron reduction inverts the helicity of copper complexes formed from derivatives of S-methylcysteine and methioninol. The change in conformation of the organic ligand is followed in the exciton-coupled circular dichroism (ECCD) spectra of the complexes.
Methionine and its derivatives increase bladder excitability by inhibiting stretch-dependent K+ channels.
Baker, S.A. et al.
British Journal of Pharmacology, 53, 1259-1271 (2008)

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