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A7384

Sigma-Aldrich

Agaric acid

Synonym(s):

2-Hydroxy-1,2,3-nona­decane­tricarboxylic acid, Agaricic acid, Agaricin

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About This Item

Empirical Formula (Hill Notation):
C22H40O7
CAS Number:
666-99-9
Molecular Weight:
416.55
EC Number:
211-566-5
MDL number:
MFCD00002665
UNSPSC Code:
12352201
PubChem Substance ID:
24891123
NACRES:
NA.25

form

powder

SMILES string

CCCCCCCCCCCCCCCCC(C(O)=O)C(O)(CC(O)=O)C(O)=O

InChI

1S/C22H40O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20(25)26)22(29,21(27)28)17-19(23)24/h18,29H,2-17H2,1H3,(H,23,24)(H,25,26)(H,27,28)

InChI key

HZLCGUXUOFWCCN-UHFFFAOYSA-N

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Application

Agaric acid (Agaricic acid), an inducer of mitochondrial permeability transition (MPT), is used to study the MPT process at the level of the ADP and ATP exchange via the adenine nucleotide carrier/translocase.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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L Wojtczak et al.
Journal of bioenergetics and biomembranes, 31(5), 447-455 (2000-02-01)
Nonesterified long-chain fatty acids have long been known as uncouplers of oxidative phosphorylation. They are efficient protonophores in the inner mitochondrial membrane but not so in artificial phospholipid membranes. In the un-ionized form, they undergo a rapid spontaneous transbilayer movement
Hai-Ling Zhang et al.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 28(4), 486-491 (2006-09-26)
To evaluate the effects of arginine modified chitosan or hexadecylated modified chitosan as gene carriers on the cellular uptake by vascular smooth muscle cells and its in vitro cytotoxicity. METHODS Plasmid DNA was labeled with alpha-32P-dATP and complexed with the
Agaric acid.
R A Freedland et al.
Methods in enzymology, 72, 497-506 (1981-01-01)
Z X Xu et al.
Biochimica et biophysica acta, 1044(1), 70-76 (1990-05-01)
Fetal lung fatty-acid synthase and choline-phosphate cytidylyltransferase activities are increased by glucocorticoids. There is evidence that the hormone increases synthesis of fatty-acid synthase but only increases the catalytic activity of the cytidylyltransferase. Free fatty acids and a number of phospholipids
The effects of specific lipogenic substrates and metabolic inhibitors on de novo fatty acid synthesis in isolated hepatocytes from chow-fed female rats.
R S Newton et al.
Archives of biochemistry and biophysics, 204(1), 379-386 (1980-10-01)
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