L-lactate dehydrogenase A chain (LDHA), also known as Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, and encoded by the gene name LDHA/ PIG19, is a member of the LDH/MDH superfamily and LDH family. Mutations in LDHA have been assoicated with Glycogen storage disease 11 (GSD11), which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
Immunogen
KLH-conjugated linear peptide corresponding to human LDH-A.
Application
Anti-LDH-A, clone 5D2.1 is an antibody against LDH-A for use in WB, IH.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected LDH-A in human breast cancer sections and human kidney tissue.
Research Category Apoptosis & Cancer
Research Sub Category Apoptosis - Additional
Quality
Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected LDH-A in 10 µg of HeLa cell lysate.
Target description
~37 kDa observed
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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