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Guanidine hydrochloride

Name: Guanidine hydrochloride
Brand: MM

Synonym(s):

Guanidine Hydrochloride, Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride

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About This Item

Linear Formula:

NH₂C(=NH)NH₂ · HCl

CAS Number:

50-01-1

Molecular Weight:

95.53

NACRES:

NA.21

UNSPSC Code:

12352107

Beilstein/REAXYS Number:

3591990

MDL number:

MFCD00013026

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Properties

description

Merck USA index - 14 4562

Quality Segment

100

mp

180-185 °C (lit.)

density

1.3 g/cm³ (lit.)

application(s)

advanced drug delivery

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

Description

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

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This Item	G4505	137272	369075
Millipore 369079 Guanidine hydrochloride	Sigma-Aldrich G4505 Guanidine hydrochloride	SAFC 137272 Guanidine hydrochloride	Millipore 369075 Guanidine Hydrochloride
description -	description ≥99% (titration), organic base and chaeotropic agent	description EMPROVE^® EVOLVE	description ULTROL^® Grade, ≥99% (titration), protein denaturant for purification of proteins, nucleic acids, and mRNA
description Merck USA index - 14 4562	description -	description -	description Merck USA index - 14, 4562
density 1.3 g/cm³ (lit.)	density 1.3 g/cm³ (lit.)	density 1.3 g/cm³ (lit.)	density -
mp 180-185 °C (lit.)	mp 180-185 °C (lit.)	mp 180-185 °C (lit.)	mp -
Quality Level 100	Quality Level 200, 400	Quality Level 400	Quality Level 100
application(s) advanced drug delivery	application(s) -	application(s) -	application(s) -

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pictograms

GHS07

signalword

Warning

hcodes

H302 + H332,H315,H319

pcodes

P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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