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Merck

HTR2A

5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

Synonyms:
5-HT2A, HTR2
Species:
UniProtKB ID:
Gene ID:
  • Human(3356) Summary: This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(15558) 5-hydroxytryptamine (serotonin) receptor 2A
  • Rat(29595) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • dog(403882) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • naked mole-rat(101708395) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • Horse(100009685) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • chicken(428070) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic guinea pig(100135545) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • domestic cat(101081108) 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
  • cow(407230) 5-hydroxytryptamine (serotonin) receptor 2A

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Small Molecule - Agonist

Product Number
Description
Species
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
2,2-Diphenylethylamine, 96%,
Species
rat
M100907, ≥98% (HPLC),
Species
human
SR-46349 hemifumarate salt, ≥98% (HPLC),
Species
human
Paliperidone, ≥98% (HPLC),
Species
human
4-Benzylpiperidine, 99%,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Serotonin 2A (5-HT2A) Receptor (22-41) Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
mouse, rat, sheep
Application
Anti-Serotonin receptor 2A/HTR2A Antibody, clone 9B11.1, clone 9B11.1, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Phenethylamine, 99%,
Species
rat, mouse, human
Phenethylamine, ≥99%,
Species
rat, mouse, human
Phenethylamine, purified by redistillation, ≥99.5%,
Species
rat, mouse, human
Mifepristone, ≥98%,
Species
human, mouse, rat
Harmaline, ≥95%,
Species
human, rat

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
Mifepristone, ≥98%,
Species
human, mouse, rat

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Htr2a,
Species
mouse