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46958

Supelco

Retinyl acetate

analytical standard

Synonym(s):

Retinol acetate, Vitamin A acetate

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About This Item

Empirical Formula (Hill Notation):
C22H32O2
CAS Number:
Molecular Weight:
328.49
Beilstein:
1915439
EC Number:
MDL number:
UNSPSC Code:
12164500
PubChem Substance ID:

Pricing and availability is not currently available.

grade

analytical standard

Quality Level

CofA

current certificate can be downloaded

feature

standard type fat soluble vitamin

packaging

ampule of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

57-58 °C

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

-10 to -25°C

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General description

Retinyl acetate is a naturally occurring long-chain fatty acid ester of retinol (Vitamin A). Retinyl acetate is suitable for use in the retention identification of the analyte when using HPLC and GC. Not intended for use as an activity reference standard.

Application

The analytical standard can also be used as follows:
  • Simultaneous determination of nine major fat-soluble vitamins― retinyl acetate, retinyl palmitate, retinol, α-tocopherol, α-tocopheryl acetate, cholecalciferol, ergocalciferol, phylloquinone, menaquinone in various commercial food product samples by supercritical fluid chromatography combined with mass spectrometric detection
  • Optimization of a supercritical fluid chromatographic method (SFC) for the simultaneous estimation of fat-soluble vitamins (FSVs) in hemp seed oil and waste fish oil samples, in combination with a diode array detector (DAD)
  • High-performance liquid chromatographic (HPLC) separation and quantification of β-carotene and vitamin A and E esters in infant formulae samples with fluorescence detection (FLD)
  • Analysis of cooking oil samples for the determination of fat-soluble vitamins and carotenoids using an ultra-performance convergence chromatography (UPC2) method
  • Multi-residue estimation of vitamin A and its derivatives in seven cosmetic product samples by liquid chromatography coupled with UV detection

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

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    Natalia Cernicchiaro et al.
    Foodborne pathogens and disease, 7(9), 1071-1081 (2010-05-27)
    Alteration of the gastro-intestinal tract through manipulation of cattle diets has been proposed as a preharvest control measure to reduce fecal shedding of Escherichia coli O157:H7. The objective of this study was to examine the effects of the energy source's
    Tadao Maeda et al.
    Investigative ophthalmology & visual science, 50(9), 4368-4378 (2009-05-02)
    Mice lacking retinal pigment epithelium-specific 65-kDa protein (RPE65) develop retinopathy and blindness resembling Leber congenital amaurosis. Effects of 9-cis-retinyl acetate (9-cis-R-Ac) on visual function and retinopathy progression were tested in Rpe65(-/-) mice. Young C57Bl/6 mice were given 9-cis-R-Ac in each
    Kajal Babamiri et al.
    Aesthetic surgery journal, 30(1), 74-77 (2010-05-06)
    A wide range of cosmeceutical products are available on the market currently, but evidence to support their use is often lacking in the literature. Specifically, there is a substantial amount of evidence supporting the efficacy of tretinoin in photoaging, but
    Akiko Maeda et al.
    The Journal of biological chemistry, 284(22), 15173-15183 (2009-03-24)
    Exposure to bright light can cause visual dysfunction and retinal photoreceptor damage in humans and experimental animals, but the mechanism(s) remain unclear. We investigated whether the retinoid cycle (i.e. the series of biochemical reactions required for vision through continuous generation
    Tadao Maeda et al.
    Human molecular genetics, 18(12), 2277-2287 (2009-04-03)
    Inactivating mutations in the retinoid isomerase (RPE65) or lecithin:retinol acyltransferase (LRAT) genes cause Leber congenital amaurosis (LCA), a severe visual impairment in humans. Both enzymes participate in the retinoid (visual) cycle, the enzymatic pathway that continuously generates 11-cis-retinal, the chromophore

    Protocols

    Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

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