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P0880

Sigma-Aldrich

Pro-Gly

≥98% (TLC), suitable for cell culture

Synonym(s):

L-prolyl-glycine

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About This Item

Empirical Formula (Hill Notation):
C7H12N2O3
CAS Number:
2578-57-6
Molecular Weight:
172.18
MDL number:
MFCD00022391
UNSPSC Code:
12352202
PubChem Substance ID:
24898135
NACRES:
NA.26

product name

Pro-Gly,

Assay

≥98% (TLC)

Quality Level

200

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

application(s)

cell analysis

storage temp.

−20°C

SMILES string

OC(=O)CNC(=O)[C@@H]1CCCN1

InChI

1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1

InChI key

RNKSNIBMTUYWSH-YFKPBYRVSA-N

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Related Categories

Biochem/physiol Actions

PRO-GLY is a dipeptide that has previously been shown to prevent progression of diabetes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shigeo Hayakawa et al.
Journal of the American Chemical Society, 129(25), 7936-7949 (2007-06-07)
We report a combined experimental and computational study of the proline effect in model dipeptides Pro-Gly and Gly-Pro. Gas-phase protonated peptide ions were discharged by glancing collisions with potassium or cesium atoms at 3 keV collision energies, and the peptide
Feng-Chun Wu et al.
The Journal of organic chemistry, 74(13), 4812-4818 (2009-05-23)
Tetrapeptides, containing a terminated primary amine and conformationally restricted D-Pro-Gly or D-Pro-Aib (2-aminoisobutanoic acid) segment as a strongly beta-turn-nucleating element, were designed and synthesized with condensation of N-module dipeptides with C-module dipeptides in solution. They were first applied to catalyze
Z Dzakula et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 135(2), 454-465 (1999-01-08)
Analytical expressions have been derived that translate uncertainties in distance constraints (obtained from NMR investigations) into uncertainties in atom positions in the maximum likelihood (ML) structure consistent with these inputs. As a test of this approach, a comparison was made
A Hagting et al.
The Journal of biological chemistry, 269(15), 11391-11399 (1994-04-15)
Lactococcus lactis takes up di- and tripeptides via a proton motive force-dependent carrier protein. The gene (dtpT) encoding the di-tripeptide transport protein of L. lactis was cloned by complementation of a dipeptide transport-deficient and proline auxotrophic Escherichia coli strain. Functional
L A Andreeva et al.
Bulletin of experimental biology and medicine, 153(5), 651-654 (2012-11-01)
Intranasal administration of regulatory peptide PRG to rats against the background of persistent hyperglycemia improves blood antiplatelet and anticoagulant-fibrinolytic potential and normalizes blood sugar in comparison with the corresponding parameters in control animals that did not receive the peptide. The
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