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G7753

Sigma-Aldrich

Glycol chitosan

≥60% (titration), crystalline

Synonym(s):

Glycol chitin, deacetylated

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25
Pricing and availability is not currently available.

form

crystalline

Quality Level

mol wt

degree of polymerization ≥400

concentration

≥60% (titration)

storage temp.

−20°C

Application

Glycol chitosan increases membrane permeability and leakage in Glycine max Harosoy 63w cells. [1]

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

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Gianni Ciofani et al.
International journal of nanomedicine, 7, 19-24 (2012-01-26)
Boron nitride nanotubes (BNNTs) have attracted huge attention in many different research fields thanks to their outstanding chemical and physical properties. During recent years, our group has pioneered the use of BNNTs for biomedical applications, first of all assessing their
D H Young et al.
Plant physiology, 70(5), 1449-1454 (1982-11-01)
Treatment of suspension-cultured Glycine max cv Harosoy 63 cells with soluble chitosan (20-500 micrograms per milliliter) increased membrane permeability as shown by leakage of electrolytes, protein, and UV absorbing material. Severe damage to the cell membrane by chitosan (100 and
Yong-Su Song et al.
Microbial pathogenesis, 129, 277-283 (2019-03-03)
To investigate the temperature requirements of chitosanase activity, as well as the degradation patterns generated by enzyme-induced chitosan oligomer hydrolysis, Pedobacter sp. PR-M6 was inoculated onto 0.5% colloidal chitosan medium agar plates. Cell growth was higher at 30 °C than at
Navneet Kaur et al.
Carbohydrate polymers, 237, 116170-116170 (2020-04-04)
Poly (lactide-co-glycolide) (PLGA) nanoparticles surface functionalized with water soluble glycol chitosan (GC) and carboxymethyl chitosan (CMC) has been studied for their drug (Paclitaxel and Doxorubicin) loading, yield, cellular uptake, serum protein adsorption and hemocompatibility. It was observed that Paclitaxel (Ptxl)
Beom Ryong Kang et al.
Carbohydrate polymers, 260, 117799-117799 (2021-03-14)
Bacillus amyloliquefaciens strain PPL shows a potential for the control of phytopathogenic fungi. In the present study, upon growing the strain PPL on various forms of chitosan (0.5 % powder, 0.1 % soluble, and 0.15 % colloidal) as the carbon

Questions

1–7 of 7 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Is the product considered deacetylated and is the 'degree of polymerization' specification given in a number of units?

    1 answer
    1. The material is indeed considered deacetylated. The molecular weight specification is given in terms of the number of monomeric units (greater than or equal to 400), but it often measures at 2000 units or higher. Recent lots (066K1894, 046K1080, 105K1648, and 065K1306) all have an average molecular weight of approximately 400,000. This is based on a monomer molecular weight of 203 and a degree of polymerization of 2000.

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  4. What is the degree of substitution for ethylene glycol in the product?

    1 answer
    1. The degree of substitution of ethylene glycol is not determined.

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  5. It states that the degree of polymerization is over 400, but are more than 400 units continuously combined based on the chitosan unit?

    1 answer
    1. The polymerization degree is at minimum is 400. Please review the lot specific Certificate of Analysis for this value: https://www.sigmaaldrich.com/certificates/COFA/G7/G7753/G7753-BULK________SLBW9324__.pdf.

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  6. What is the degree of deacetylation?

    1 answer
    1. This product is considered to be deacetylated. Chitosan is the deacetylated form of chitin. The degree of acetylation is not determined for this product, but is expected to be approximately 90%.

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  7. How is the titration performed?

    1 answer
    1. The titration protocol is proprietary, however it is a colloidal titration method involving the use of potassium polyvinyl sulfate.

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