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A9887

Sigma-Aldrich

Aflatoxin B2

≥98% (HPLC), powder, mycotoxin

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About This Item

Empirical Formula (Hill Notation):
C17H14O6
CAS Number:
7220-81-7
Molecular Weight:
314.29
Beilstein:
1355115
EC Number:
230-618-8
MDL number:
MFCD00078140
UNSPSC Code:
12352200
PubChem Substance ID:
24891405
NACRES:
NA.77

product name

Aflatoxin B2,

form

powder

Quality Level

200

storage temp.

2-8°C

SMILES string

COc1cc2O[C@H]3OCC[C@H]3c2c4OC(=O)C5=C(CCC5=O)c14

InChI

1S/C17H14O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h6,8,17H,2-5H2,1H3/t8-,17+/m0/s1

InChI key

WWSYXEZEXMQWHT-WNWIJWBNSA-N

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General description

Aflatoxin B2/AFB2 is a toxic mycotoxin.

Application

Aflatoxin B2 has been used as a standard in a study to find out aflatoxins in various foods, spices and feedstuffs by high performance liquid chromatography (HPLC). It has also been used as a standard to determine aflatoxins in honey by HPLC.

Biochem/physiol Actions

Aflatoxin B2 is a hepatocarcinogen. Food contaminant produced by Aspergillus flavus, a common soil fungus. Aflatoxin B2/AFB2 may have dangerous hepatotoxic, teratogenic and carcinogenic actions on various forms of livestock.

Warning

Possibly carcinogenic.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 1B - Muta. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Induction of mitochondria-mediated apoptosis and PI3K/Akt/mTOR-mediated autophagy by aflatoxin B2 in hepatocytes of broilers
Chen B, et al.
Oncotarget, 7(51), 84989-84989 (2016)
A STUDY ON AFLATOXINS IN VARIOUS FOODS, SPICES AND FEEDSTUFFS BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
OZ, T. Y. V.
The ISME Journal, 31, 11-16 (2016)
Bacillaceae spores, fungi and aflatoxins determination in honey Esporos de Bacillaceae, fungos e aflatoxinas em mel
Martins H M, et al.
RN (2003)
Sharaf S Omar et al.
Foods (Basel, Switzerland), 9(5) (2020-05-24)
In Jordan as in other worldwide countries, mycotoxins are considered a serious national problem in food supplies. As a result, almost all nations are setting and adopting different regulations targeting the control of mycotoxins levels in the domestic food supply
Fernanda Cosme et al.
Foods (Basel, Switzerland), 9(12) (2020-12-06)
Aflatoxins B1 and B2 are two highly toxic mycotoxins that have been sometimes found in wines. Currently, no technological solution is available to reduce or eliminate aflatoxins from wines when they are present. Therefore, this work aims to study the
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