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Key Documents

10830

Sigma-Aldrich

(+)-Arabinogalactan

≥80% (HPLC), from larch wood

Synonym(s):

Polyarabinogalactan

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About This Item

CAS Number:
9036-66-2
EC Number:
232-910-0
MDL number:
MFCD00062638
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

larch wood

Quality Level

100

Assay

≥80% (HPLC)

form

solid

impurities

≤15% water

color

white to beige

mp

>200 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear to slightly turbid, colorless to slightly brownish-yellow

storage temp.

room temp

InChI

1S/C20H36O14/c1-7-11(23)18(12(24)9(4-21)32-7)34-20-15(27)17(29-3)13(25)10(33-20)6-31-19-14(26)16(28-2)8(22)5-30-19/h7-27H,4-6H2,1-3H3

InChI key

SATHPVQTSSUFFW-UHFFFAOYSA-N

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Application

Larch Arabinogalactan, a plant-derived biopolymer, is an excellent dietary fiber that has been shown to increase the production of short-chain fatty acids, principally butyrate and propionate, and to decrease the generation and absorption of ammonia. Larch arabinogalactan can stimulate natural killer (NK) cell cytotoxicity, enhance other functional aspects of the immune system, and inhibit the metastasis of tumor cells to the liver.

Biochem/physiol Actions

Dietary fiber that enhances immune system function by stimulating natural killer (NK) cell activity.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Arabinogalactan, a plant polysaccharide, as a new tool for pharmacon clathration.
T G Tolstikova et al.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 433, 247-248 (2010-08-17)
G S Kelly
Alternative medicine review : a journal of clinical therapeutic, 4(2), 96-103 (1999-05-08)
Larch arabinogalactan is composed of greater than 98-percent arabinogalactan, a highly branched polysaccharide consisting of a galactan backbone with side-chains of galactose and arabinose sugars. Larch arabinogalactan is an excellent source of dietary fiber, and has been approved as such
Susi Burgalassi et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 23(6), 541-550 (2007-11-16)
The aim of the present study was to investigate the corneal protective and healing properties of arabinogalactan (AG), a natural polysaccharide present in conifers of the genus Larix (Larch). AG was tested in comparison with other two polysaccharides possessing well-established
Xiaoge Gao et al.
Glycoconjugate journal, 29(4), 159-165 (2012-05-09)
The pH-modified citrus pectin (MCP) has been demonstrated to inhibit galectin-3 in cancer progression. The components and structures of MCP related to this inhibition remained unknown. In this paper, we fractionated MCP on DEAE-cellulose column into a homogenous neutral fraction
Cristiane H Baggio et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 67(7-8), 405-410 (2012-09-29)
Type II arabinogalactan (AG) is a polysaccharide found in Maytenus ilicifolia (Celastraceae), a plant reputed as gastroprotective. Oral and intraperitoneal administration of the AG protected rats from gastric ulcers induced by ethanol. No alteration of mechanisms related to acid gastric
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