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Key Documents

O9882

Sigma-Aldrich

Octyl β-D-glucopyranoside

BioXtra, ≥98% (GC)

Synonym(s):

n-Octyl glucoside, OGP

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About This Item

Empirical Formula (Hill Notation):
C14H28O6
CAS Number:
Molecular Weight:
292.37
Beilstein:
84118
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.21

description

non-ionic

Quality Level

product line

BioXtra

Assay

≥98% (GC)

form

powder

mol wt

micellar avg mol wt 25,000

aggregation number

84

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.2%

CMC

20-25 mM (20-25°C)

transition temp

cloud point >100 °C

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.003%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.1%
Na: ≤0.1%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

−20°C

SMILES string

CCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1

InChI key

HEGSGKPQLMEBJL-RKQHYHRCSA-N

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Application

Octyl β --D-glucopyranoside has been used as a component of aqueous buffer containing NaCl, HEPES and chromogenic substrate for use in trypsin assays
Non-ionic, dialyzable detergent for the solubilization and isolation of membrane proteins. Has been shown to increase the resolution of proteins in 2D gels.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.
Bioorganic & Medicinal Chemistry Letters, 18(6), 2114-2121 (2008)
Alison Kan et al.
Journal of proteomics, 79, 299-304 (2012-12-04)
A high degree of optimisation is required in native co-immunoprecipitation (co-IP) experiments with added challenges for low-abundant membrane proteins and masking by IgG molecules. Although in vivo tagged-protein purification avoids the IgG masking problem, modifying the terminus of the protein
Zheng-Zheng Zou et al.
Bioresource technology, 118, 425-430 (2012-06-19)
A new β-glucosidase (DtGH) representing 40% identity with an apple seed glycosidase (ASG) was cloned from Dictyoglomus thermophilum. DtGH showed extremely high thermostability in aqueous solution, with half-lives of 533, 44, and 5 h measured at 70, 80 and 90
Baris E Polat et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(2), 250-260 (2011-11-22)
The synergism between low-frequency sonophoresis (LFS) and chemical penetration enhancers (CPEs), especially surfactants, in transdermal enhancement has been investigated extensively since this phenomenon was first observed over a decade ago. In spite of the identifying that the origin of this
Zahrabatoul Mosapour Kotena et al.
Journal of molecular modeling, 19(2), 589-599 (2012-09-14)
Density functional theory calculations on two glycosides, namely, n-octyl-β-D-glucopyranoside (C(8)O-β-Glc) and n-octyl-β-D-galactopyranoside (C(8)O-β-Gal) were performed for geometry optimization at the B3LYP/6-31G level. Both molecules are stereoisomers (epimers) differing only in the orientation of the hydroxyl group at the C4 position.

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