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33996

Supelco

Ethopabate

VETRANAL®, analytical standard

Synonym(s):

Methyl 4-acetamido-2-ethoxybenzoate, Ethopabate, Ethyl pabate

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About This Item

Empirical Formula (Hill Notation):
C12H15NO4
CAS Number:
Molecular Weight:
237.25
Beilstein:
2808914
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCOc1cc(NC(C)=O)ccc1C(=O)OC

InChI

1S/C12H15NO4/c1-4-17-11-7-9(13-8(2)14)5-6-10(11)12(15)16-3/h5-7H,4H2,1-3H3,(H,13,14)

InChI key

GOVWOKSKFSBNGD-UHFFFAOYSA-N

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General description

Ethopabate is an antibiotic used as a coccidiostat in poultry feeds.

Application

Ethopabate may be used as a reference standard in the determination of ethopabate in feed samples using solid phase extraction with high performance liquid chromatography (SPE-HPLC).
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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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V A Thorpe
Journal - Association of Official Analytical Chemists, 63(5), 981-984 (1980-09-01)
Medicated feeds (pelleted or mash) containing guarantees of carbadox, furazolidone, nitrofurazone, and ethopabate are pretreated with water, extracted with 95% dimethylformamide overnight at room temperature, cleaned up on a column of alumina, and injected into a high pressure liquid chromatograph
Rodrigo H M M Granja et al.
Journal of AOAC International, 91(6), 1483-1487 (2009-02-11)
Ethopabate is frequently used in the prophylaxis and treatment of coccidiosis in poultry. Residues of this drug in food present a potential risk to consumers. A simple, rapid, and sensitive column high-performance liquid chromatographic (HPLC) method with UV detection for
L R Schronk et al.
Journal - Association of Official Analytical Chemists, 60(5), 1048-1050 (1977-09-01)
A high pressure liquid chromatographic (HPLC) method is described for determining ethopabate in poultry feeds. Feed samples containing ethopabate are finely ground, extracted 30 min by sonification with methanol-water (80 + 20), and filtered. The extract is cleaned up on
T Nagata et al.
Journal - Association of Official Analytical Chemists, 68(1), 27-28 (1985-01-01)
A liquid chromatographic (LC) method is described for determination of ethopabate residues in chicken tissues. The drug is extracted from tissues with acetonitrile, and the extract is concentrated to 2-3 mL. This aqueous solution is rinsed with ethyl acetate and
C A Kan et al.
Tijdschrift voor diergeneeskunde, 114(2), 76-82 (1989-01-15)
Amprolium may be used as a coccidiostat in rearing hens and is a therapeutical agent used in laying hens. As a result of cross contamination, low amprolium levels may occur in feed. Feed containing a concentration of amprolium ranging from

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