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21620

Supelco

Disperse Blue 124

for microscopy

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12171500
NACRES:
MA.02

grade

for microscopy

Quality Level

application(s)

environmental

format

neat

InChI

1S/C16H19N5O4S/c1-4-20(7-8-25-12(3)22)13-5-6-14(11(2)9-13)18-19-16-17-10-15(26-16)21(23)24/h5-6,9-10H,4,7-8H2,1-3H3

InChI key

HMAJVAFLGGPIPN-UHFFFAOYSA-N

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General description

Disperse Blue (DB) 124 is a strong clothing dye sensitizer. It is also an important textile dye allergen.

Application

DB 124 was used during testing the sensitizing potential of the dye using loose-fit coculture-based sensitization assay (LCSA).

Other Notes

Dye standard for the assay of allergy-releasing dyes in textiles

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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B M Hausen
Contact dermatitis, 28(3), 169-173 (1993-03-01)
9 cases of allergic contact dermatitis due to black "velvet" fabrics, mostly leggings, are reported. In all cases, the 2 disperse dyes Blue 106 and 124 were shown to be the responsible contact sensitizers. Preparation of a chloroform extract and
Nonpruritic contact dermatitis from disperse blue dyes.
Aaron Wong et al.
Dermatitis : contact, atopic, occupational, drug, 22(5), 278-280 (2012-06-02)
Z Caliskaner et al.
Human & experimental toxicology, 31(1), 101-103 (2011-10-27)
Disperse blue (DB) 106 and DB 124 are the most frequent fabric dye allergens inducing textile dermatitis, but contact allergy to them may easily undiagnosed because the clinical picture usually needs high index of suspicion. We present the case of
Clothing dye dermatitis masquerading as (coexisting) mimosa allergy.
J D Guin et al.
Contact dermatitis, 40(1), 45-45 (1999-02-03)
P Komericki et al.
Journal of the American Academy of Dermatology, 45(3), 456-458 (2001-08-21)
The diagnosis of purpura pigmentosa progressiva in a female patient had to be changed to purpuric contact dermatitis after patch testing with textile dyes. A modified patch test performed in the area in which most of her skin lesions were

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