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P-076

Supelco

Propofol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C12H18O
CAS Number:
2078-54-8
Molecular Weight:
178.27
EC Number:
200-659-6
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

CC(C)c1cccc(C(C)C)c1O

InChI

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3

InChI key

OLBCVFGFOZPWHH-UHFFFAOYSA-N

Gene Information

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Related Categories

General description

Propofol, also known as Diprivan®, is a short-acting, hypnotic drug intravenously administered for the induction and maintenance of general anesthesia and sedation. This certified reference solution is suitable for a variety of uses from forensic and forensic toxicology analysis to drug monitoring in plasma or whole blood.

Application


  • Thin-layer chromatography combined with diode laser thermal vaporization inductively coupled plasma mass spectrometry.: This study explores the integration of thin-layer chromatography (TLC) with diode laser thermal vaporization and inductively coupled plasma mass spectrometry (ICP-MS). The research demonstrates the application of TLC aluminum sheets with cellulose in separating complex mixtures. The combined technique offers enhanced sensitivity and specificity for analyzing trace elements and isotopic composition in various samples (Bednařík et al., 2014).


Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Diprivan is a registered trademark of Abraxis Bioscience, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Primum non nocere or how to resolve drug-induced respiratory depression.
Albert Dahan et al.
Anesthesiology, 118(6), 1261-1263 (2013-05-24)
Mami Sasao-Takano et al.
Anesthesia progress, 60(2), 60-66 (2013-06-15)
The magnetic resonance imaging (MRI) room is a special environment. The required intense magnetic fields create unique problems with the use of standard anesthesia machines, syringe pumps, and physiologic monitors. We have recently experienced 2 oral maxillofacial surgery cases requiring
The effective effect-site propofol concentration for induction in morbidly obese patients using total body weight with a new pharmacokinetic model.
Natalia F de la Fuente et al.
Anesthesia and analgesia, 117(1), 283-284 (2013-06-22)
C Creeley et al.
British journal of anaesthesia, 110 Suppl 1, i29-i38 (2013-06-05)
Exposure of the fetal or neonatal non-human primate (NHP) brain to isoflurane or ketamine for 5 h causes widespread apoptotic degeneration of neurones, and exposure to isoflurane also causes apoptotic degeneration of oligodendrocytes (OLs). The present study explored the apoptogenic
Jeffrey W Sall et al.
Anesthesia and analgesia, 117(1), 65-67 (2013-05-02)
Propofol has been reported to have high stability in glass and relatively high stability up to 24 hours in polyvinyl chloride-based medical plastics. Recent publications have observed the effects of propofol on cells and tissues grown in culture. Many cell
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