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Key Documents

W328707

Sigma-Aldrich

Glycine

99%, FCC

Synonym(s):

Aminoacetic acid, Aminoethanoic acid, Glycocoll

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About This Item

Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
FEMA Number:
3287
Beilstein:
635782
EC Number:
Council of Europe no.:
4118
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
17.034
NACRES:
NA.21

biological source

synthetic

Quality Level

Agency

meets purity specifications of JECFA

reg. compliance

FCC
FDA 21 CFR 170.50
FDA 21 CFR 172.320
FDA 21 CFR 172.812

Assay

99%

form

crystalline powder

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

odorless

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

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Application


  • From Collagen Mimetics to Collagen Hybridization and Back.: This study explores the use of glycine-rich collagen mimetics in developing hybridized collagen structures, offering insights into biocompatible materials and tissue engineering applications (Ratnatilaka Na Bhuket et al., 2024).

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
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The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
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A simple and versatile methodology using high-performance liquid chromatography (HPLC) with fluorimetric detection was developed to simultaneously determine d-serine along with other metabolically related neuroactive amino acids in the glutamatergic system: L-serine, L-glutamate, L-glutamine, and glycine. On-column sensitivity was in

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