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KITALYSIS-CUCN

Sigma-Aldrich

KitAlysis High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit-Pack of 2

Synonym(s):

Copper Catalyzed C-N Coupling Kit

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.22

reaction suitability

core: palladium
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

Application

Screening kit for Copper C-N Cross-Coupling Reactions. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.

Step-by-Step Guide for KitAlysis High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit

Downloadable experimental excel sheet

Each kit contains 2 customizable screening sets that include the following components:
  • 24 (6 x 4) pre-weighed ligands in glass vials loaded with stir bars, topped with cap mat
  • Potassium phosphate: 4 pre-weighed vials with product labels and lids
  • CuI (soluble source) in preweighed vial
  • 4 degassed anhydrous solvents (dioxane, DMAc, toluene, and DMSO) in ampules
  • 1 internal standard
  • 2 KitAlysis 24-Well reaction block replacement films
  • 8 stir bars for stock solutions
  • Ampule cracker

Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

  • Designed and tested by synthetic chemists.
  • Easily run 24-microscale reaction in parallel.
  • Suggested conditions: 10 μmol reactions with 1 μmol catalyst (10 mol%) 0.1 M concentration, and 3 equiv. base.
  • Customizable and downloadable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

Flash Point(F)

39.2 °F

Flash Point(C)

4 °C


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Articles

KitAlysis High-Throughput Screening Kits provide solution to efficiently identify or optimize suitable catalytic reaction conditions. Chemist can rapidly run 24 unique micro scale reactions in parallel with tailored conditions.

Protocols

KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

KitAlysis™ Cu C-N (Buchwald-Hartwig) cross-coupling high-throughput screening kit. Detailed Set-Up User Guide and a downloadable excel file for calculations.

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