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708887

Sigma-Aldrich

4-Aminophenylboronic acid hydrochloride

95%

Synonym(s):

4-Aminobenzeneboronic acid hydrochloride

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About This Item

Linear Formula:
C6H8BNO2 · HCl
CAS Number:
80460-73-7
Molecular Weight:
173.41
MDL number:
MFCD03001333
UNSPSC Code:
12352103
PubChem Substance ID:
329762832
NACRES:
NA.22

Quality Level

100

Assay

95%

form

powder

mp

195-200 °C

SMILES string

Cl.Nc1ccc(cc1)B(O)O

InChI

1S/C6H8BNO2.ClH/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,9-10H,8H2;1H

InChI key

QBYGJJSFMOVYOA-UHFFFAOYSA-N

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General description

May contain varying amounts of anhydride

Application

4-Aminophenylboronic acid hydrochloride can be used to prepare:
  • The modified reduced graphene composite material used as a sugar sensor to detect the analyte in fruit juice.
  • The modified carbon electrode adsorbed with aminophenol, used for the detection of NADH and H2O2.
  • The boron, nitrogen, and sulfur-doped carbon dot sensor, which in turn can be used for the detection of ascorbic acid.

Reactant for:
  • Preparation of chromen-4-ones as DNA-dependent protein kinase inhibitors

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Qi Wang et al.
Biosensors & bioelectronics, 50, 331-337 (2013-07-25)
A sensitive electrochemical active interface for sugar sensing based on the specific boronic acid-diol binding was established. The sensing matrix was formed by stirring a suspension of graphene oxide (GO) with 4-aminophenylboronic acid (APBA). The resulting composite consists of a
Sabrina Belbekhouche et al.
Colloids and surfaces. B, Biointerfaces, 177, 416-424 (2019-02-25)
Glucose-responsive multilayer capsules have been produced through the layer-by-layer deposition of biodegradable polymers based on hydrogen bonding. The used polymers are alginate derivative and polyvinylpyrolidone (PVPON). Concentration-dependent glucose responsiveness was reached through chemical modification of alginate, selected as polyanion, with
A dual-mode sensor for colorimetric and ?turn-on? fluorescent detection of ascorbic acid
Liu Y, et al.
Dyes and Pigments, 149, 491-497 (2018)
Sun Dal Kim et al.
Science advances, 4(10), eaau1956-eaau1956 (2018-11-07)
The key component currently missing for the next generation of transparent and flexible displays is a high-performance polymer material that is flexible, while showing optical and thermal properties of glass. It must be transparent to visible light and show a
Tsan-Yu Tsai et al.
Biomaterials science, 9(3), 985-999 (2020-12-11)
Nanocomposite double-network hydrogels (ncDN hydrogels) are recently introduced to address the limitations of traditional DN hydrogels, such as the lack of diversity in the network structure and the restricted functionalities. However, two challenges remain, including the time-consuming preparation and the
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