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Quality Level
Assay
99%
bp
105 °C/0.5 mmHg (lit.)
mp
62-64 °C (lit.)
SMILES string
COC1=CC(=O)OC1
InChI
1S/C5H6O3/c1-7-4-2-5(6)8-3-4/h2H,3H2,1H3
InChI key
VOYDEHILKLSVNN-UHFFFAOYSA-N
Gene Information
human ... CYP1A2(1544)
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General description
4-Methoxy-2(5H)-furanone is a furanone. 4-Methoxy-2(5H)-furanone is isolated from Narthecium asiaticum maxim leave samples and is reported to cause nephrotoxicity in cattle.
Application
4-Methoxy-2(5H)-furanone may be used as starting reagent in the synthesis of 5-alkylidene 4-methoxy-2(5H)-furanone.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Natural toxins, 7(6), 317-319 (2000-12-21)
Two samples of Narthecium asiaticum Maxim leaves collected in Japan were found to contain 103 microg(-1) and 160 microg g(-1) dry matter of 3-methoxy-2(5H)-furanone respectively. 3-Methoxy-2(5h)-furanone was suggested to be the toxic principle of N. asiaticum causing nephrotoxicity in cattle
Toward the synthesis of the antibiotic tetrodecamycin.
Tetrahedron Letters, 41(51), 9977-9980 (2000)
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