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283215

Sigma-Aldrich

Poly(allylamine hydrochloride)

average Mw ~17,500 (GPC vs. PEG std.)

Synonym(s):

PAA HCl, PAH

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About This Item

Linear Formula:
[CH2CH(CH2NH2 · HCl)]n
CAS Number:
71550-12-4
EC Number:
415-050-2
MDL number:
MFCD00084396
UNSPSC Code:
12162002
PubChem Substance ID:
24857093
NACRES:
NA.23

form

solid

Quality Level

200

mol wt

average Mw ~17,500 (GPC vs. PEG std.)

SMILES string

Cl.NCC=C

InChI

1S/C3H7N/c1-2-3-4/h2H,1,3-4H2

InChI key

VVJKKWFAADXIJK-UHFFFAOYSA-N

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General description

Poly(allylamine hydrochloride) (PAH) is a water-soluble weak-base and a biodegradable polymer.

Application

Poly(allylamine hydrochloride) can be used as a starting material to prepare:
  • Chitosan/PAH polymer blend films by solution casting technique. These films can be employed in injectable drug delivery systems and tissue generation.
  • Cross-linked amino-modified graphene oxide for the removal of Cr(IV) from aqueous solutions.
  • Polyelectrolyte multilayers(PEMs) by the layer-by-layer method. These PEMs can be used to prepare controlled drug delivery systems and coatings with controlled cell adhesion properties.
Used to make redox hydrogel-modified electrodes for measuring enzyme responses.

Features and Benefits

  • Excellent environmental stability
  • Water-soluble
  • Low cost

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000388329
0000356142
0000356143
0000356142
0000356143

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B Marzec et al.
Journal of structural biology, 208(2), 127-136 (2019-08-23)
Coccolithophores are marine phytoplankton that are among the most prolific calcifiers widespread in Earth's oceans, playing a crucial role in the carbon cycle and in the transport of organic matter to the deep sea. These organisms produce highly complex mineralized
Yiyao Liu et al.
Expert opinion on drug delivery, 9(10), 1197-1207 (2012-09-27)
Technologies to increase tissue vascularity are critically important to the fields of tissue engineering and cardiovascular medicine. Angiogenic factors, like VEGF, have been widely investigated to induce vascular endothelial cell proliferation and angiogenesis for establishing a vascular network. However, effective
L Minati et al.
International journal of pharmaceutics, 438(1-2), 45-52 (2012-09-11)
Gold nanoparticles functionalized with doxorubicin and stabilized with multilayers of degradable polyelectrolyte were allowed to age in aqueous medium in vitro in order to show the possibility of drug release in cellular environment. The chemico-physical characteristics of the nanoparticles are
Xin Gao et al.
International journal of nanomedicine, 7, 4037-4051 (2012-08-14)
We designed dual-functional nanoparticles for in vivo application using a modified electrostatic and covalent layer-by-layer assembly strategy to address the challenge of assessment and treatment of hormone-refractory prostate cancer. Core-shell nanoparticles were formulated by integrating three distinct functional components, ie
Magdalena Oćwieja et al.
Langmuir : the ACS journal of surfaces and colloids, 29(11), 3546-3555 (2013-01-17)
Systematic studies of silver particle deposition kinetics under diffusion transport on poly(allylamine hydrochloride) (PAH) modified mica were carried out. Monolayer coverage, quantitatively determined by AFM and SEM, was regulated within broad limits by adjusting the deposition time and the ionic
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Articles

Layer-by-Layer (LbL) Assembly, A "Gentle Yet Flexible" Method Toward Functional Biomaterials

Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

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