281506

Methyl 4-methoxyacetoacetate

97%

• Linear Formula: CH₃OCH₂COCH₂COOCH₃
• CAS Number: 41051-15-4
• Molecular Weight: 146.14
• Beilstein: 1761215
• EC Number: 255-188-9
• MDL number: MFCD00010183
• UNSPSC Code: 12352100
• PubChem Substance ID: 24856977
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• refractive index: n20/D 1.431 (lit.)
• bp: 89 °C/8.5 mmHg (lit.)
• density: 1.129 g/mL at 25 °C (lit.)
• functional group: ester; ether; ketone
• SMILES string: COCC(=O)CC(=O)OC
• InChI: 1S/C6H10O4/c1-9-4-5(7)3-6(8)10-2/h3-4H2,1-2H3
• InChI key: QGBPKJFJAVDUNC-UHFFFAOYSA-N

Description

Application

Methyl 4-methoxyacetoacetate has been used in generation of a small focused library of diversely functionalized dihydropyrimidine derivatives via one-pot three-component Biginelli cyclocondensation of β-ketoesters, aldehydes and (thio)ureas.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 188.6 °F - closed cup
• Flash Point(C): 87 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves