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Key Documents

278998

Sigma-Aldrich

2-Amino-5-hydroxybenzoic acid

98%

Synonym(s):

5-Hydroxyanthranilic acid

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About This Item

Linear Formula:
HOC6H3(NH2)CO2H
CAS Number:
Molecular Weight:
153.14
Beilstein:
2803663
MDL number:
UNSPSC Code:
12352106
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

247 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Nc1ccc(O)cc1C(O)=O

InChI

1S/C7H7NO3/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3,9H,8H2,(H,10,11)

InChI key

HYNQTSZBTIOFKH-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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[Diabeton in the treatment of stage I nephroangiopathy in insulin-dependent diabetes mellitus].
E P Kashirina et al.
Sovetskaia meditsina, (1)(1), 68-69 (1991-01-01)
V K Velikov et al.
Terapevticheskii arkhiv, 63(10), 44-49 (1991-01-01)
Hemocoagulation was examined in 477 diabetes mellitus patients. Whatever the disease type, severity, duration and the intensity of microvascular complications, diabetes mellitus was discovered to be marked by the development of chronic intravascular blood microcoagulation associated with primary hyperactivation of
T A Buĭdina et al.
Sovetskaia meditsina, (7)(7), 14-16 (1991-01-01)
Newly detected noninsulin--dependent diabetes mellitus is shown to have changes in phospholipid structure of erythrocytic membranes: a fall in total phospholipids, sphingomyelin, phosphatidylcholine, phosphatidic acid, a trend to increasing lysophosphatidylcholine. The shifts go in parallel with lipid peroxidation activation. Carbohydrate
Deze Kong et al.
Science advances, 6(44) (2020-11-01)
Chalcone synthase (CHS) canonically catalyzes carbon-carbon bond formation through iterative decarboxylative Claisen condensation. Here, we characterize a previously unidentified biosynthetic capability of SlCHS to catalyze nitrogen-carbon bond formation, leading to the production of a hydroxycinnamic acid amide (HCAA) compound. By
Alexander von Tesmar et al.
Cell chemical biology, 24(10), 1216-1227 (2017-09-12)
In vitro reconstitution and biochemical analysis of natural product biosynthetic pathways remains a challenging endeavor, especially if megaenzymes of the nonribosomal peptide synthetase (NRPS) type are involved. In theory, all biosynthetic steps may be deciphered using mass spectrometry (MS)-based analyses of

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