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Key Documents

211281

Sigma-Aldrich

9-Phenanthrol

technical grade

Synonym(s):

9-Hydroxyphenanthrene

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About This Item

Empirical Formula (Hill Notation):
C14H10O
CAS Number:
Molecular Weight:
194.23
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

mp

139-143 °C (lit.)

SMILES string

Oc1cc2ccccc2c3ccccc13

InChI

1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H

InChI key

DZKIUEHLEXLYKM-UHFFFAOYSA-N

Application

9-Phenanthrol was used to investigate C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes.

Biochem/physiol Actions

9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ana Mrejeru et al.
The Journal of physiology, 589(Pt 10), 2497-2514 (2011-04-14)
Nigral dopamine neurons are transiently activated by high frequency glutamatergic inputs relaying reward-predicting sensory information. The tonic firing pattern of dopamine cells responds to these inputs with a transient burst of spikes that requires NMDA receptors. Here, we show that
T Grand et al.
British journal of pharmacology, 153(8), 1697-1705 (2008-02-26)
TRPM4 and TRPM5 are calcium-activated non-selective cation channels with almost identical characteristics. TRPM4 is detected in several tissues including heart, kidney, brainstem, cerebral artery and immune system whereas TRPM5 expression is more restricted. Determination of their roles in physiological processes
Eric C Lin et al.
Frontiers in cellular neuroscience, 11, 182-182 (2017-07-18)
Temporal lobe epilepsy is characterized by recurrent seizures in one or both temporal lobes of the brain; some
A Kuznetsova et al.
Journal of the American Chemical Society, 123(43), 10699-10704 (2001-10-25)
Single-walled nanotubes (SWNTs) produced by plasma laser vaporization (PLV) and containing oxidized surface functional groups have been studied for the first time with NEXAFS. Comparisons are made to SWNTs made by catalytic synthesis over Fe particles in high-pressure CO, called
Amy C Smith et al.
American journal of physiology. Cell physiology, 304(5), C467-C477 (2013-01-11)
Members of the transient receptor potential (TRP) channel superfamily, including the Ca(2+)-activated monovalent cation-selective TRP melastatin 4 (TRPM4) channel, have been recently identified in the urinary bladder. However, their expression and function at the level of detrusor smooth muscle (DSM)

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