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164194

Sigma-Aldrich

Heptafluorobutyric acid

98%

Synonym(s):

Edman Reagent No. 3, HFBA, Perfluorobutyric acid

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About This Item

Linear Formula:
CF3CF2CF2COOH
CAS Number:
375-22-4
Molecular Weight:
214.04
Beilstein:
1426882
EC Number:
206-786-3
MDL number:
MFCD00004171
UNSPSC Code:
12352100
PubChem Substance ID:
24850063
NACRES:
NA.22

vapor density

7 (vs air)

Quality Level

200

vapor pressure

~10 mmHg ( 25 °C)

Assay

98%

form

liquid

refractive index

n20/D 1.3 (lit.)

bp

120 °C/755 mmHg (lit.)

density

1.645 g/mL at 25 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)C(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C4HF7O2/c5-2(6,1(12)13)3(7,8)4(9,10)11/h(H,12,13)

InChI key

YPJUNDFVDDCYIH-UHFFFAOYSA-N

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General description

Perfluorobutyric acid is an effective additive for zinc electrodeposition.

Application

Perfluorobutyric acid was used as mobile phase modifier for enhancement of selectivity in the HPLC analysis of histone proteins. It was used as ion pairing reagent in preparative and analytical reserved phase HPLC of underivatised peptides.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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M Naldi et al.
Journal of chromatography. A, 1129(1), 73-81 (2006-08-05)
The application of reversed-phase high-pressure liquid chromatography under gradient conditions and electrospray ion trap mass spectrometry (LC-ESI-MS) to the analysis of global modification levels of core histones is described. The optimised LC-ESI-MS method was applied for the first time to
Zinc electrowinning from acidic sulphate solutions Part IV: effects of perfluorocarboxylic acids.
Tripathy BC, et al.
Journal of Electroanalytical Chemistry, 565(1), 49-56 (2004)
D R Harding et al.
International journal of peptide and protein research, 18(2), 214-220 (1981-08-01)
This report describes the successful use of the ether soluble, ion pairing reagents perfluoropropoinic and perfluorobutyric acid in the preparative and analytical reserved phase HPLC of underivatised peptides. The preparative separation of a 1-g sample of Pyr-His-Gly, the proposed anorexigenic
Huilun Chen et al.
International journal of environmental research and public health, 17(4) (2020-02-23)
Perfluoroalkyl carboxylic acids (PFCAs) are some of the most significant pollutants in human serum, and are reported to be potentially toxic to humans. In this study, the binding mechanism of PFCAs with different carbon lengths to human serum albumin (HSA)
Marta Llorca et al.
The Science of the total environment, 431, 139-150 (2012-06-12)
Water has been identified as one of the main routes of human exposure to perfluoroalkyl substances (PFASs). This work assessed the presence of 21 PFASs along the whole water cycle using a new fast and cost effective analytical method based
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