139122

Isobutyryl chloride

98%

• Synonym(s): 2-Methylpropanoic acid chloride, 2-Methylpropionyl chloride, 2-Propylcarbonyl chloride, Chloro isopropyl ketone, Isobutyroyl chloride, Isopropanecarbonyl chloride
• Linear Formula: (CH₃)₂CHCOCl
• CAS Number: 79-30-1
• Molecular Weight: 106.55
• Beilstein: 605393
• EC Number: 201-194-1
• MDL number: MFCD00000717
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848392
• NACRES: NA.22

Properties

• vapor pressure: 0.07 mmHg ( 20 °C)
• Assay: 98%
• form: liquid
• refractive index: n20/D 1.407 (lit.)
• bp: 91-93 °C (lit.)
• mp: −90 °C (lit.)
• density: 1.017 g/mL at 25 °C (lit.)
• functional group: acyl chloride
• SMILES string: CC(C)C(Cl)=O
• InChI: 1S/C4H7ClO/c1-3(2)4(5)6/h3H,1-2H3
• InChI key: DGMOBVGABMBZSB-UHFFFAOYSA-N

Description

General description

Isobutyryl chloride reacts with guanine to yield N(2)-isobutyrylguanine.

Application

Isobutyryl chloride was used in the synthesis of fully isobutyramide terminated hyperbranched polyethylenimines. It was used in the separation and identification of shikonin and its ester derivatives in the root epidermis of Echium italicum L. It was employed as versatile acylating agent for the ketimine derivatives of α-amino esters, nucleosides and pyrroles.

Versatile acylating agent for the ketimine derivatives of α-amino esters, nucleosides, and pyrroles.

Safety Information

• Pictograms: GHS02,GHS05
• Signal Word: Danger
• Hazard Statements: H225,H314
• Precautionary Statements: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Flam. Liq. 2 - Skin Corr. 1A
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 46.4 °F - closed cup
• Flash Point(C): 8 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves