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P5338

Sigma-Aldrich

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt

Powder

Synonym(s):

5,6-Diphenyl-3-(2-pyridyl)-1,2,4-triazine-4′,4″-disulfonic acid sodium salt, PDT disulfonate

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About This Item

Empirical Formula (Hill Notation):
C20H13N4NaO6S2
CAS Number:
Molecular Weight:
492.46
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt, BioXtra

product line

BioXtra

Quality Level

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

≥300 °C

anion traces

chloride (Cl-): ≤0.1%

cation traces

Al: ≤0.001%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.001%
Pb: ≤0.001%
Zn: ≤0.0005%

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].OS(=O)(=O)c1ccc(cc1)-c2nnc(nc2-c3ccc(cc3)S([O-])(=O)=O)-c4ccccn4

InChI

1S/C20H14N4O6S2.Na/c25-31(26,27)15-8-4-13(5-9-15)18-19(14-6-10-16(11-7-14)32(28,29)30)23-24-20(22-18)17-3-1-2-12-21-17;/h1-12H,(H,25,26,27)(H,28,29,30);/q;+1/p-1

InChI key

ZGVNYCXXBQPDPQ-UHFFFAOYSA-M

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General description

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt is also known as ferrozine.

Application

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt (ABTS) has been used in the ferene-s assay for the accurate determination of intracellular iron from iron oxide nanoparticles.
It has also been used in ABTS radical scavenging assay to determine the antioxidant activity of honey samples.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Wance J J Firdaus et al.
The FEBS journal, 273(13), 3076-3093 (2006-07-05)
We recently reported that the transient expression of polyglutamine tracts of various size in exon 1 of the huntingtin polypeptide (httEx1) generated abnormally high levels of intracellular reactive oxygen species that directly contributed to cell death. Here, we compared the
Chana Kranzler et al.
Environmental microbiology, 13(11), 2990-2999 (2011-09-13)
In many aquatic environments the essential micronutrient iron is predominantly complexed by a heterogeneous pool of strong organic chelators. Research on iron uptake mechanisms of cyanobacteria inhabiting these environments has focused on endogenous siderophore production and internalization. However, as many
Emanuel Vamanu
Journal of biomedicine & biotechnology, 2012, 565974-565974 (2012-07-11)
Exopolysaccharides (EPS) and internal (intracellular) polysaccharides (IPS) obtained from the Pleurotus ostreatus M2191 and PBS281009 cultivated using the batch system revealed an average of between 0.1-2 (EPS) and 0.07-1.5 g/L/day (IPS). The carbohydrate analysis revealed that the polysaccharides comprised 87-89% EPS
James R Reed et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(11), 2060-2066 (2010-08-04)
Heme oxygenase 1 (HO-1) uses molecular oxygen and electrons from NADPH cytochrome P450 reductase to convert heme to CO, ferrous iron, and biliverdin (BV). Enzymatic studies with the purified 30-kDa form of HO-1 routinely use a coupled assay containing biliverdin
William W Bennett et al.
Talanta, 88, 490-495 (2012-01-24)
The recently developed colorimetric diffusive equilibration in thin films (DET) technique for the in situ, high-resolution measurement of iron(II) in marine sediments is optimized to allow measurement of the higher iron concentrations typical of freshwater sediment porewaters. Computer imaging densitometry

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