901910
Pyridyl disulfide-poly(ethylene glycol)-b-poly(ε-caprolactone)
PEG average Mn 5000, PCL average Mn 5000
Synonym(s):
PDS-PEG-PCL, PEG-b-PCL, PEG-PCL
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About This Item
Linear Formula:
C10H14NOS3[C2H4O]n[C6H10O2]mH
UNSPSC Code:
12352005
NACRES:
NA.23
Recommended Products
form
powder or solid
mol wt
PCL average Mn 5000
PEG average Mn 5000
color
white to off-white
PDI
≤1.3 (by GPC)
storage temp.
−20°C
Application
Pyridyl disulfide-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block.These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The PDS functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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