696439

(S)-Ethyl piperidine-3-carboxylate

97%

• Synonym(s): (S)-3-Piperidinecarboxylic acid ethyl ester, (S)-Ethyl nipecotate
• Empirical Formula (Hill Notation): C₈H₁₅NO₂
• CAS Number: 37675-18-6
• Molecular Weight: 157.21
• MDL number: MFCD00792499
• UNSPSC Code: 12352100
• PubChem Substance ID: 329761828
• NACRES: NA.22

Properties

• Assay: 97%
• form: liquid
• refractive index: n20/D 1.471
• density: 1.043 g/mL at 25 °C
• functional group: ester
• SMILES string: CCOC(=O)[C@H]1CCCNC1
• InChI: 1S/C8H15NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h7,9H,2-6H2,1H3/t7-/m0/s1
• InChI key: XIWBSOUNZWSFKU-ZETCQYMHSA-N

Description

Application

Reactant for synthesis of:

• DPP-4 inhibitors
• JAK2 inhibitors
• Serotonin and noradrenaline reuptake inhibitors
• Human tryptase inhibitors
• Anti-thrombotic nicecotamides

Reactive for oxidative C-arylation of free (NH)-heterocycles via direct (sp3) C-H bond functionalization

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H318
• Precautionary Statements: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 170.1 °F
• Flash Point(C): 76.7 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves