CD3I is isotopically deuterium- enriched reagent of methyl iodide.
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Glycosylation is an important post-translational modification of proteins. Many diseases, such as cancer, have proved to be related to aberrant glycosylation. High throughput quantitative methods have gained attention recently in the study of glycomics. With the development of high-resolution mass
Rapid communications in mass spectrometry : RCM, 27(8), 865-877 (2013-03-16)
Mass spectrometry based comparative glycomics is essential for disease biomarker discovery. However, developing a reliable quantification method is still a challenging task. We here report an isotopic labeling strategy employing stable isotopic iodomethane for comparative glycomic profiling by liquid chromatography/electrospray
International journal of biological macromolecules, 50(1), 263-269 (2011-11-22)
Five water-soluble chitosan derivatives were carried out by quaternizing either iodomethane or N-(3-chloro-2-hydroxypropyl) trimethylammonium chloride (Quat188) as a quaternizing agent under basic condition. The degree of quaternization (DQ) ranged between 28±2% and 90±2%. The antifungal activity was evaluated by using
We describe here the determination of the alkylation rate of a set of organic superbases by iodomethane in DMF using a microfluidic continuous flow reactor. Surprisingly, log k(Alkylation) follows the inverse trend of pK(BH+) of the base. Mayr's equation allows
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 985-992 (2011-05-11)
Electronic absorption and fluorescence spectra of eight hemicyanine dyes were recorded at room temperature in several solvents of different polarity. The spectral data were analyzed using the theory of solvatochromism, based on a dielectric continuum description of the solvent and
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