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L-α-Phosphatidylcholine

Name: <SC>L</SC>-α-Phosphatidylcholine
Brand: SIGMA

egg yolk, Type XIII-E, 100 mg/mL in ethanol, solution

Synonym(s):

1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC

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About This Item

CAS Number:

8002-43-5

UNSPSC Code:

51321705

NACRES:

NA.25

Beilstein/REAXYS Number:

5209585

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Properties

biological source

egg yolk

Quality Segment

200

type

Type XIII-E

assay

≥99% (TLC)

form

solution

concentration

100 mg/mL in ethanol

functional group

phospholipid

lipid type

phosphoglycerides

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1

InChI key

JLPULHDHAOZNQI-ZTIMHPMXSA-N

Description

General description

Phosphatidylcholine is the major membrane phospholipid in eukaryotic cells. This structural component of the cellular membrane is the source of the bioactive lipids lysophosphatidylcholine, phosphatidic acid, diacylglycerol, lysophosphatidylcholine, platelet-activating factor, and arachidonic acid.

Application

L-α-Phosphatidylcholine has been used in differential lipid partitioning experiments of xenobiotics and natural compounds to determine trioleoylglycerol (TG) and phosphatidylcholine (PC) coefficients (KTG/PC) for partitioning of lipophilic chemicals.

Biochem/physiol Actions

Phosphatidylcholine serves as a reservoir for several lipid messengers. Phosphatidylcholine is used for the preparation of vesicle suspensions, commonly called liposomes or monolayers.

A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.

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This Item	61755	P2772	P5638
Sigma-Aldrich P4279 L-α-Phosphatidylcholine	Sigma-Aldrich 61755 L-α-Phosphatidylcholine	Sigma-Aldrich P2772 L-α-Phosphatidylcholine	Sigma-Aldrich P5638 L-α-Phosphatidylcholine
description egg yolk, Type XIII-E, 100 mg/mL in ethanol, solution	description egg yolk, ~60% (TLC)	description egg yolk, Type XI-E, 100 mg/mL in chloroform, ≥99%, solution	description from soybean, Type II-S, 14-29% choline basis
assay ≥99% (TLC)	assay -	assay ≥99%	assay -
biological source egg yolk	biological source egg yolk	biological source egg yolk	biological source soybean
functional group phospholipid	functional group phospholipid	functional group phospholipid	functional group phospholipid
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C
form solution	form solid	form solution	form powder or solid
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200

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Pictograms

GHS02,GHS07

Signal Word

Danger

Hazard Codes

H225,H319

Precautionary Statements

P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

60.8 °F

Flash Point (°C)

16 °C

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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