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RAB0600

Sigma-Aldrich

Human A2M / Alpha-2-macroglobulin ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 ng/mL
standard curve range: 12.29-3000 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... A2M(2)

General description

Human α-2-macroglobulin (α2M/A2M), a large tetrameric glycoprotein, is abundantly seen in plasma. It possesses anti-proteinase activity. A2M acts as a vital indicator in detecting thrombotic diseases. It plays a major role in coagulation and fibrinolysis systems. α2M may have the potential to be a new biomarker and therapeutic target for steroid-induced femoral head necrosis (SINFH). The A2M ELISA kit can be used for the quantitative measurement of α-2-macroglobulin in cell culture supernatants, plasma, and serum.
The A2M ELISA kit provides for the quantitative measurement of Alpha-2-macroglobulin in Cell Culture Supernatants, Plasma and Serum.

Application

Human A2M/Alpha-2-macroglobulin ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) to confirm the presence of α-2-macroglobulin (A2M) in the analyzed saliva pools.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Shan-Hong Fang et al.
Orthopaedic surgery, 11(3), 481-486 (2019-06-28)
The present study aimed to identify the relationship of α-2-macroglobulin and microvascular vessel pathology with steroid-induced femoral head necrosis in the Southeast Chinese population. This study enrolled 40 patients diagnosed with steroid-induced necrosis of the femoral head. Patients had various
Swati Dixit et al.
Protein and peptide letters, 28(3), 315-322 (2020-09-23)
Aldicarb is a carbamate pesticide commercially used in potato crop production. Once it enters human body, it interacts with diverse proteins and other substances. Aldicarb is toxic to human health and it is also a cholinesterase inhibitor, which prevents the
Sarah A Ingelse et al.
PloS one, 14(1), e0210172-e0210172 (2019-01-18)
Experimental acute lung injury models are often used to increase our knowledge on the acute respiratory distress syndrome (ARDS), however, existing animal models often do not take into account the impact of specific fluid strategies on the development of lung
Romina Hernández-Olivos et al.
Scientific reports, 11(1), 15646-15646 (2021-08-04)
There are currently no preventative options for recurrent aphthous stomatitis, and the only available treatments are palliative. This is partly due to a poor understanding of its etiopathogenesis. In this case-control study, we characterized the salivary proteome of patients with

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