00895

Dextran

analytical standard, for GPC, 410,000

• Linear Formula: [C₆H₁₀O₅]_n
• CAS Number: 9004-54-0
• EC Number: 232-677-5
• MDL number: MFCD00130935
• UNSPSC Code: 12352201
• NACRES: NA.24

Properties

• grade: analytical standard; for GPC
• Quality Level: 100
• form: powder or crystals
• mol wt: M_n ~236,300; M_p ~276,500; M_w ~409,800
• analyte chemical class(es): oligosaccharides
• technique(s): gel permeation chromatography (GPC): suitable
• Mw/Mn: ~1.73
• application(s): food and beverages
• InChI: 1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
• InChI key: FZWBNHMXJMCXLU-UHFFFAOYSA-N

Description

General description

Dextran (mol. wt. 410,000) belongs to the family of neutral polysaccharides, which are recognized as contaminants in sugar processing and other food production industries. These are composed of chains of D-glucose units connected by alpha-(1-6) linkages of varying lengths. They are found as bacterial extracellular polysaccharides and reportedly synthesized from sucrose by beneficial lactic acid bacteria, such as Leuconostoc mesenteroides and Lactobacillus brevis. They are incorporated in bakery products to improve the crumb texture, softness, and loaf volume, as stabilizers and additives in confectionery, flavor extract, icing compositions, beverages including soft drinks, milk, etc.

Application

• Dextran in Drug Delivery: A study in "Journal of Biomedical Materials Research Part A" demonstrated how dextran, a biopolymer, enhances wound healing. It focused on collagen-polyurethane-dextran hydrogels, which inhibit inflammation and promote collagen fibrillogenesis, making dextran crucial for tissue engineering and medical applications (Aguayo-Morales et al., 2024).


• Dextran as a Blood Plasma Expander: Research in "Redox Biology" highlighted the role of dextran in reducing systemic iron overload stress. This study provides insights into how dextran′s properties are beneficial for managing conditions like anemia and other blood volume deficiencies (Zhao et al., 2024).


• Dextran in Cell Culture: An article in ""International Journal of Biological Macromolecules"" explored the use of dextran-based antibacterial hydrogels. These gels are used for fluorescent sensors in bioanalytical applications, showing dextran′s utility in cell culture and microbial monitoring (Bai et al., 2024).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves