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Key Documents

EZRMGH

Millipore

Rat/Mouse Growth Hormone ELISA Kit

measures and quantifies GH levels in 10 μL serum, plasma or cell culture supernatent

Synonym(s):

Growth hormone, Somatotrophin

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

Rat/Mouse Growth Hormone ELISA, This Rat/Mouse Growth Hormone ELISA is used to measure & quantify Growth Hormone levels in Metabolism & Endocrine & Cell Signaling research.

Quality Level

200

species reactivity

rat, mouse

packaging

kit of 1 × 96 wells

parameter

10 μL sample volume (4hr assay)

assay range

accuracy: 96-101%
linearity: 97-118%
sensitivity: 0.07 ng/mL
(10 μl sample size)
standard curve range: 0.07-50 ng/mL

technique(s)

ELISA: suitable

input

sample type serum
sample type cell culture supernatant
sample type plasma (K2 EDTA)

UniProt accession no.

P01244
P06880

application(s)

research use

detection method

colorimetric (450nm/590nm)

shipped in

wet ice

storage temp.

2-8°C

General description

Growth Hormone (GH) is a 23 kDa circulating pituitary hormone, Rat GH shares approximately 97% homology with mouse GH and 65% homology with human GH in its protein sequence. The main target of action for growth hormone is the central nervous system. In animal models, this hormone exerts neuroprotective effects against neurodegenerative stimuli and prevents neural loss on hypoxic-ischaemic damage. Thus, a reduced level of growth hormone with aging affects brain function and leads to memory and cognitive impairments. This Rat/Mouse Growth Hormone ELISA is used to measure & quantify Growth Hormone levels in Metabolism & Endocrine & Cell Signaling research.

Application

Rat/Mouse Growth Hormone ELISA has been used to measure or quantify growth hormone levels in mice blood samples, xenograft model, and plasma samples.

Other Notes

Room temperature 3.5 hour, 10 μl serum, plasma, or tissue culture medium

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Certificates of Analysis (COA)

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Iñigo Azcoitia et al.
Neurobiology of aging, 26(5), 697-703 (2005-02-15)
Decline of growth hormone (GH) with aging is associated to memory and cognitive alterations. In this study, the number of neurons in the hilus of the dentate gyrus has been assessed in male and female Wistar rats at 3, 6
Reproductive dysfunction and decreased gnRH neurogenesis in a Mouse Model of cHARGE syndrome.
Layman WS, Hurd EA, Martin DM
Human Molecular Genetics null
Andre Sarmento-Cabral et al.
The Journal of endocrinology, 248(1), 31-44 (2020-10-29)
A reduction in hepatocyte growth hormone (GH)-signaling promotes non-alcoholic fatty liver disease (NAFLD). However, debate remains as to the relative contribution of the direct effects of GH on hepatocyte function vs indirect effects, via alterations in insulin-like growth factor 1
Naomi Morozumi et al.
Peptides, 32(5), 1001-1007 (2011-02-05)
Ghrelin is an endogenous ligand for growth hormone secretagogue receptor 1a (GHS-R1a), and consists of 28 amino acid residues with octanoyl modification at Ser(3). The previous studies have revealed that N-terminal part of ghrelin including modified Ser(3) is the active
Supriya Sen et al.
Nature communications, 4, 1336-1336 (2013-01-10)
SR family RNA binding proteins regulate splicing of nascent RNAs in vitro but their physiological role in vivo is largely unexplored, as genetic deletion of many SR protein genes results in embryonic lethality. Here we show that SRSF3HKO mice carrying
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