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850396P

Avanti

20:1 (Cis) PC

1,2-dieicosenoyl-sn-glycero-3-phosphocholine, powder

Synonym(s):

1,2-di-(11Z-eicosenoyl)-sn-glycero-3-phosphocholine; PC(20:1(11Z)/20:1(11Z))

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About This Item

Empirical Formula (Hill Notation):
C48H92NO8P
CAS Number:
61596-54-1
Molecular Weight:
842.22
UNSPSC Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850396P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 850396P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCC/C=C\CCCCCCCC)=O)=O

General description

20:1 (Cis) PC (1,2-dieicosenoyl-sn-glycero-3-phosphocholine) is a lipid derivative having a phosphocholine backbone. It has two 20 carbon fatty acid chains, each having one cis double bond at the 11th carbon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

20:1 (Cis) PC (1,2-dieicosenoyl-sn-glycero-3-phosphocholine) may be used:
  • as an internal standard for mass spectrometric analysis
  • to prepare large multilamellar vesicles for proteoliposome generation
  • to study the effects of the lipid chain length on 6-bromoacetyl-2-dimethylaminonaphthalene (BADAN) fluorescence parameters

Biochem/physiol Actions

Phosphatidylcholine (PC) is known to participate in the fusion and transport of membranes.

Packaging

5 mL Clear Glass Sealed Ampule (850396P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Metabolic Heavy Isotope Labeling to Study Glycerophospholipid Homeostasis of Cultured Cells
Hanninen S, et al.
Bio-protocol, 7(9) (2017)
Larisa E Cybulski et al.
Current biology : CB, 20(17), 1539-1544 (2010-08-14)
Thermosensors are ubiquitous integral membrane proteins found in all kinds of life. They are involved in many physiological roles, including membrane remodeling, chemotaxis, touch, and pain [1-3], but, the mechanism by which their transmembrane (TM) domains transmit temperature signals is
Rob B M Koehorst et al.
Biophysical journal, 94(10), 3945-3955 (2008-02-01)
The work presented here describes a new and simple method based on site-directed fluorescence labeling using the BADAN label that permits the examination of protein-lipid interactions in great detail. We applied this technique to a membrane-embedded, mainly alpha-helical reference protein
Miao-Miao Zhou et al.
Lipids in health and disease, 15(1), 135-135 (2016-08-26)
Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well.

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