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R2751

Sigma-Aldrich

Ruthenium Red

Powder

Synonym(s):

Ammoniated ruthenium oxychloride

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About This Item

Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
11103-72-3
Molecular Weight:
786.35
Colour Index Number:
77800
MDL number:
MFCD00011479
UNSPSC Code:
12171500
PubChem Substance ID:
24278675
NACRES:
NA.47

product name

Ruthenium Red, Technical grade

Quality Level

200

Assay

34-39% (RUTHENIUM, ICP)

form

powder

solubility

water: 10 mg/mL

εmax

≥150 at 533-534 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]

InChI

1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6

InChI key

ZXYSDUPLHOJIOR-UHFFFAOYSA-H

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General description

Ruthenium Red is a hexavalent polysaccharide stain. It inhibits mitochondrial Ca2+ uniporter. It is a capsaicin antagonist and blocks vanilloid receptor-1 (VR-1)-coupled ion channels.

Application

Ruthenium Red has been used for microscopic characterization of cotton tip morphology. It has also been used as a TRPV2 channel blocker.
Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL4574
BCCM5302
BCCJ8828
BCCH7874
BCCG1965

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Ruthenium red as a capsaicin antagonist.
Amann R and Maggi CA
Life Sciences, 49(12) (1991)
Cotton fiber tips have diverse morphologies and show evidence of apical cell wall synthesis
Michael R. Stiff and Candace H. Haigler
Scientific Reports (2016)
Rachel E Field et al.
Neuron, 106(5), 842-854 (2020-03-28)
Excitation in neural circuits must be carefully controlled by inhibition to regulate information processing and network excitability. During development, cortical inhibitory and excitatory inputs are initially mismatched but become co-tuned or balanced with experience. However, little is known about how
Marco Schlepütz et al.
PloS one, 7(10), e47344-e47344 (2012-10-12)
The peripheral airway innervation of the lower respiratory tract of mammals is not completely functionally characterized. Recently, we have shown in rats that precision-cut lung slices (PCLS) respond to electric field stimulation (EFS) and provide a useful model to study
Identification of an Aspartic Residue in the P-loop of the Vanilloid Receptor That Modulates Pore Properties*
Carolina Garcia-MArtinez
The Journal of Biological Chemistry (2000)
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