AB5735
Anti-Neurofilament M Antibody
Chemicon®, from chicken
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
chicken
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human, rat
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... NEFM(4741)
mouse ... Nefm(18040)
rat ... Nefm(24588)
Specificity
Neurofilament M (NF-M)
Immunogen
Recombinant C-terminal extension of rat NF-M, the so-called KE segment.
Application
Anti-Neurofilament M Antibody detects level of Neurofilament M & has been published & validated for use in WB & IC.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Western blot: 1:5,000-1:10,000
Immunocytochemistry: 1:1,000-1:2,000
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:1,000-1:2,000
Optimal working dilutions must be determined by the end user.
Physical form
Chicken IgY. Liquid containing ~5 mM sodium azide.
Format: Purified
Storage and Stability
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
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Storage Class Code
10 - Combustible liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Niliksha Gunewardene et al.
Stem cells international, 2016, 1781202-1781202 (2016-03-12)
Induced pluripotent stem cells (iPSCs) may serve as an autologous source of replacement neurons in the injured cochlea, if they can be successfully differentiated and reconnected with residual elements in the damaged auditory system. Here, we explored the potential of
Víctor Hugo Cornejo et al.
Cell reports, 30(13), 4505-4517 (2020-04-03)
TRPM8 is the main ion channel responsible for cold transduction in the somatosensory system. Nerve terminal availability of TRPM8 determines cold sensitivity, but how axonal secretory organelles control channel delivery remains poorly understood. Here we examine the distribution of TRPM8
Rui O Costa et al.
Cell reports, 28(4), 864-876 (2019-07-25)
Ribosomes and a subset of cellular mRNAs are trafficked into axons of developing neurons. The axonal localization of translational machinery allows new proteins to be rapidly and locally synthesized during axonal growth and pathfinding. However, in mature neurons, axonal ribosomes
Electrophysiological properties of neurosensory progenitors derived from human embryonic stem cells.
Karina Needham et al.
Stem cell research, 12(1), 241-249 (2013-11-28)
In severe cases of sensorineural hearing loss where the numbers of auditory neurons are significantly depleted, stem cell-derived neurons may provide a potential source of replacement cells. The success of such a therapy relies upon producing a population of functional
Carolina González et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(7), 1823-1828 (2016-02-04)
The regulation of the axonal proteome is key to generate and maintain neural function. Fast and slow axoplasmic waves have been known for decades, but alternative mechanisms to control the abundance of axonal proteins based on local synthesis have also
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