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P3069

Sigma-Aldrich

Poly-L-lysine–FITC Labeled

mol wt 30,000-70,000

Synonym(s):

FITC-Labeled Poly-ʟ-lysine

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About This Item

MDL number:
UNSPSC Code:
12352209
NACRES:
NA.26

form

powder

Quality Level

mol wt

precursor poly-L-lysine • HBr 30,000-70,000
30,000-70,000

extent of labeling

0.003-0.01 mol FITC per mol lysine monomer

color

yellow to orange

application(s)

cell analysis

storage temp.

−20°C

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Application


  • Application of fluorescence recovery after photobleaching to diffusion of a polyelectrolyte in a multilayer film.: This study utilizes FITC-labeled Poly-L-lysine to investigate the diffusion dynamics of polyelectrolytes in multilayer films via fluorescence recovery after photobleaching, providing insights into molecular interactions and film assembly processes (Picart C et al., 2005).

  • Detection of charges and their distribution on dialysis membranes with cationic/anionic dyes using confocal laser scanning microscopy.: This research demonstrates the use of FITC-labeled Poly-L-lysine among other dyes to detect and analyze the distribution of charges on dialysis membranes, which is crucial for improving the performance and safety of dialysis treatments (Thomaneck U et al., 1991).

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vitreous is a barrier in nonviral gene transfer by cationic lipids and polymers.
Pitkanen L, Ruponen M, et al.
Pharmaceut. Res., 20, 576-583 (2003)
Marjo Männistö et al.
The journal of gene medicine, 7(4), 466-476 (2004-12-25)
Retinal pigment epithelium (RPE) maintains the function of photoreceptors and eyesight and is an important target for gene delivery. Since in some diseases RPE cells proliferate uncontrollably, we investigated the role of cell cycle in non-viral gene delivery into a
Larry J Millet et al.
Lab on a chip, 10(12), 1525-1535 (2010-04-15)
Wiring the nervous system relies on the interplay of intrinsic and extrinsic signaling molecules that control neurite extension, neuronal polarity, process maturation and experience-dependent refinement. Extrinsic signals establish and enrich neuron-neuron interactions during development. Understanding how such extrinsic cues direct
Leena Pitkänen et al.
The AAPS journal, 6(3), e25-e25 (2005-03-12)
We investigated the permeation of liposomal and polymeric gene delivery systems through neural retina into retinal pigment epithelium (RPE) and determined the roles of various factors in permeation and subsequent uptake of the delivery systems by RPE. Anterior parts and
Alessandro Roncador et al.
Biophysical chemistry, 229, 115-122 (2017-05-10)
We report a comprehensive study of the biocompatibility and neurocompatibility of titanium dioxide films (TiO

Articles

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