Skip to Content
Merck
All Photos(1)

Documents

D1260

Sigma-Aldrich

Decamethonium bromide

crystalline

Synonym(s):

Decamethylene bis(trimethylammonium bromide), Decane-1,10-bis(trimethylammonium bromide)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3)3N(Br)(CH2)10N(Br)(CH3)3
CAS Number:
541-22-0
Molecular Weight:
418.29
Beilstein:
3728288
EC Number:
208-772-2
MDL number:
MFCD00011779
UNSPSC Code:
12352200
PubChem Substance ID:
24277833
NACRES:
NA.77

form

crystalline

Quality Level

200

color

off-white

mp

263-267 °C (lit.)

originator

GlaxoSmithKline

SMILES string

[Br-].[Br-].C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C

InChI

1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2

InChI key

HLXQFVXURMXRPU-UHFFFAOYSA-L

Gene Information

human ... CHRNA1(1134) , CHRNA10(57053) , CHRNA2(1135) , CHRNA3(1136) , CHRNA4(1137) , CHRNA5(1138) , CHRNA6(8973) , CHRNA7(1139) , CHRNA9(55584) , CHRNB1(1140) , CHRNB2(1141) , CHRNB3(1142) , CHRNB4(1143) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

Looking for similar products? Visit Product Comparison Guide

Application

Decamethonium bromide has been used to induce paralysis in duck embryo.

Biochem/physiol Actions

Decamethonium serves as a muscle relaxant and is also a neuromuscular blocking agent. It has a molecular weight of 258.4.
Nicotinic acetylcholine receptor partial agonist and neuromuscular blocking agent; depolarizes striated muscles and blocks their activity.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mesenchymal and mechanical mechanisms of secondary cartilage induction
Solem R C, et al.
Developmental Biology, 356(1), 28-39 (2011)
D Bertrand et al.
Proceedings of the National Academy of Sciences of the United States of America, 87(5), 1993-1997 (1990-03-01)
Neuronal nicotinic acetylcholine receptor of the alpha 4/non-alpha (alpha 4/n alpha) type was reconstituted in Xenopus oocytes after nuclear injection of cDNA expression vectors. Functional neuronal receptor was only formed when the two subunits alpha 4 and n alpha were
Raul Garrido-Medina et al.
Electrophoresis, 32(15), 2036-2043 (2011-07-06)
Prostate-specific antigen (PSA) is the usual biomarker for prostate cancer (PCa). However, its lack of selectivity has lead to the search for new biomarkers. PSA glycosylation seems to depend on the pathophysiological conditions of the individual. Thus, methods to separate
Borjana Mikic et al.
Annals of biomedical engineering, 32(1), 18-25 (2004-02-18)
The mechanical behavior of cartilage is intimately related to its biochemical composition, and tissue composition is known to be influenced by its local mechanical loading environment. Although this phenomenon has been well-studied in adult cartilage, few investigations have examined such
C Lee et al.
British journal of anaesthesia, 88(5), 692-699 (2002-06-18)
Of the polymethylene bismethonium congeners (C5-C12 and C18), decamethonium (C10) is the most potent neuromuscular blocking agent. We tested the hypothesis that these congeners act as straight molecules and will not bend easily in spite of the flexible connecting chain
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service